DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Arp8 and arp9

DIOPT Version :9

Sequence 1:NP_573251.1 Gene:Arp8 / 32769 FlyBaseID:FBgn0030877 Length:607 Species:Drosophila melanogaster
Sequence 2:NP_594356.1 Gene:arp9 / 2541540 PomBaseID:SPAC1071.06 Length:523 Species:Schizosaccharomyces pombe


Alignment Length:660 Identity:125/660 - (18%)
Similarity:204/660 - (30%) Gaps:252/660 - (38%)


- Green bases have known domain annotations that are detailed below.


  Fly    35 IIVIHPGSQHLR--IGRAADLNPLTLLHAVAYRRRPGASDRPHH-----------DPLLPPLDNV 86
            ||||..||.:.|  .|.|..|.|.|    :..|.|.|.:|...:           ||      ||
pombe     9 IIVIQTGSLYHRATFGLAESLEPPT----IRVRTRVGKNDNGEYVFTNKEDINMEDP------NV 63

  Fly    87 N----------------SNSGLMVEFEEQRLVVSRILQHCVVDNKNRLRVATP-PQQLAHFNRSS 134
            .                |||.:    .|::.:.|.....|.||:      .|| |.::.      
pombe    64 KTDETKVETSESTSEQPSNSNV----TEEKNMGSSFHSECKVDD------FTPLPNEIQ------ 112

  Fly   135 QAEKVPAPSGQMADEPWLDREAPVLFDDRILRLGAVDARNYDIHFPIQRGELNVHNEKGGSLQAS 199
                                                         |||||.:           ..
pombe   113 ---------------------------------------------PIQRGRV-----------VD 121

  Fly   200 MQHLERIWSYALEERLKIPLRKLGTHCAVLVVNDVYVRRHLREFVTLLLRRLGFRRC-----FLV 259
            .:.|:..|.:.....||.|......:...||: ..|...:.||..|    :..|..|     .:.
pombe   122 WEALKAFWKHLYSLLLKDPNDTTFRYPVCLVI-PTYWSLYDRELAT----QFFFEECQVPGFTIA 181

  Fly   260 QDSVASTFGAGIGYGCVVDIGAQKTSIACIEDGISQLDARVRLSYGGGDLDQVLLLLLRKCGFPY 324
            .:.:...:..||.:|.|:|||.:||.|..|.||.....|..:|..||                  
pombe   182 YEPLMGLYAIGILHGLVIDIGYEKTDITPILDGQIIFTATQQLPLGG------------------ 228

  Fly   325 RECNVQESYVDAHLLDELKEKFCHLNASVCGAQEKHFNLRKHNGQWLRYTIQVGDEALMAPLALF 389
                   .|:..||.:.|:|....|               |.:||:      |..|.:       
pombe   229 -------RYMTQHLQNLLRESLPTL---------------KSSGQY------VSKEDI------- 258

  Fly   390 HTELLNITGRTKAVFTQQAVQDQYDCEDCFDAEYLKETGRKNGVRG-------GDILQLSTSAGY 447
             |||  ...:.|.....|.|:|:.|..    .:.:|.....|.|..       |.|:....:..|
pombe   259 -TEL--FAEQVKCSEIAQVVRDEQDTA----KDPVKALTSTNNVEEEDPAEDIGKIIASGQTRAY 316

  Fly   448 QPRPQLPVTADDEELIVVDQDETISNCQSQ---LGAQTAG----GQMNSNGC---YHNGQGLVLP 502
            ..:.:.....:.|      :||...|...:   :..:..|    |:.....|   :|......:.
pombe   317 LAQKEREKNGESE------KDEKPDNTDVEFQTIAIEPLGDCIVGRERFKICEPIFHRPSNETVS 375

  Fly   503 LDQAIIQSI-NRLSSYETKRKMFGSILLVGSSAKLPGLAAWLEQRISQQVQ----SEVNVLIKGM 562
            |.:||..:| |..::|:.:..::.:|:::|..:::.|....|.|::..:.|    .|.....:|.
pombe   376 LPEAIYITIKNYAANYKRRNDLWENIIVLGCGSRIRGFRECLIQQLQFKYQLSGSLEPYYAAQGT 440

  Fly   563 DA--GMV----------------------AWK---------------GAAIM---SVLESARELW 585
            |:  ||.                      :||               |.:|:   |..||....:
pombe   441 DSILGMTTMPPTPYPALINPCKILPDYFPSWKPDAGTNAMFEELAFLGGSIVAKTSFNESVSSHY 505

  Fly   586 ISQNDWQRHG 595
            ::..::.:||
pombe   506 VTLEEYAQHG 515

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Arp8NP_573251.1 NBD_sugar-kinase_HSP70_actin 202..603 CDD:302596 89/463 (19%)
arp9NP_594356.1 COG5277 26..523 CDD:227602 117/643 (18%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5277
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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