DRSC/TRiP Functional Genomics Resources

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Protein Alignment Arp8 and POTEH

DIOPT Version :9

Sequence 1:NP_573251.1 Gene:Arp8 / 32769 FlyBaseID:FBgn0030877 Length:607 Species:Drosophila melanogaster
Sequence 2:NP_001129685.1 Gene:POTEH / 23784 HGNCID:133 Length:545 Species:Homo sapiens


Alignment Length:292 Identity:58/292 - (19%)
Similarity:95/292 - (32%) Gaps:94/292 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly   282 QKTSIACIED-GISQLDARVR----LSYGGGDLDQVLLLLLRKCGFPYRECNVQESYVDAHLLDE 341
            :|..|..::| .:::.|.:.|    |:...|:.:.|.|||.|:|              ..::||.
Human   191 RKDLIVMLKDTDMNKKDKQKRTALHLASANGNSEVVKLLLDRRC--------------QLNILDN 241

  Fly   342 LKEKFCHLNASVCGAQEKHFNLRKH----------NGQWLRYTIQVGDEALMAPLALFHTEL--L 394
             |::.....|..|...|....|.:|          ....|.|.|...|:.:...|.|:..::  .
Human   242 -KKRTALTKAVQCQEDECALMLLEHGTDPNIPDEYGNTALHYAIYNEDKLMAKALLLYGADIESK 305

  Fly   395 NITGRTKAVF-----TQQAVQ------------DQYD--------CEDCFDAEYLK--------- 425
            |..|.|..:.     .||.|:            |:|.        |  |..|..:.         
Human   306 NKHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRYGRTALILAVC--CGSASIVSLLLEQNIDV 368

  Fly   426 -------ETGRKNGV--RGGDILQL-----------STSAGYQPRPQLPVTADDEELIVVDQDET 470
                   :|.|:..|  |...|.||           .:|....|...|.:|:::|...:...:.:
Human   369 SSQDLSGQTAREYAVSSRHNVICQLLSDYKEKQILKVSSENSNPEQDLKLTSEEESQRLKGSENS 433

  Fly   471 ISNCQSQLGAQTAGG------QMNSNGCYHNG 496
            .....||......||      :|..:|..|.|
Human   434 QPEEMSQEPEINKGGDRKVEEEMKKHGSTHMG 465

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Arp8NP_573251.1 NBD_sugar-kinase_HSP70_actin 202..603 CDD:302596 58/292 (20%)
POTEHNP_001129685.1 Ank_4 180..230 CDD:290365 9/38 (24%)
ANK 1 180..208 3/16 (19%)
ANK 204..329 CDD:238125 30/139 (22%)
ANK 2 209..238 9/42 (21%)
ANK repeat 211..240 CDD:293786 9/42 (21%)
Ank_2 214..306 CDD:289560 22/106 (21%)
ANK repeat 242..273 CDD:293786 6/30 (20%)
ANK 3 242..271 6/28 (21%)
ANK 270..394 CDD:238125 23/125 (18%)
ANK repeat 275..306 CDD:293786 6/30 (20%)
ANK 4 275..304 6/28 (21%)
Ank_2 280..372 CDD:289560 17/93 (18%)
ANK repeat 308..339 CDD:293786 5/30 (17%)
ANK 5 308..337 5/28 (18%)
ANK repeat 341..372 CDD:293786 4/32 (13%)
ANK 6 341..370 4/30 (13%)
ANK 7 374..404 7/29 (24%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 406..524 13/60 (22%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5277
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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