Protein Alignment Arp8 and ACTRT2

DIOPT Version :9

• Sequence 1: NP_573251.1
• Gene: Arp8 / 32769
• FlyBaseID: FBgn0030877
• Length: 607
• Species: Drosophila melanogaster
• Sequence 2: NP_536356.3
• Gene: ACTRT2 / 140625
• HGNCID: 24026
• Length: 377
• Species: Homo sapiens
• Alignment Length: 545
• Identity: 113/545 - (20%)
• Similarity: 183/545 - (33%)
• Gaps: 183/545 - (33%)

  Fly    68 PGASDRPHHDPLLPPLDNVNS--NSGLMVEFEEQRLVVSRILQHCVVDNKNRLRVATPPQQLAHF 130
            |.|.|.|     ....||.:.  .:||..|| ..|.:||.|:.|.
Human     4 PHALDSP-----AVIFDNGSGFCKAGLSGEF-GPRHMVSSIVGHL-------------------- 42

  Fly   131 NRSSQAEKVPAPSGQMADEPWLDREAPVLFDDRILRLGAVDARNYDIHFPIQRGELNVHNEKGGS 195
                   |..|||.:...:.:...| ..|:....|:|          |.|.:||
Human    43 -------KFQAPSAEANQKKYFVGE-EALYKQEALQL----------HSPFERG----------- 78

  Fly   196 LQASMQHLERIWSYALEERLKI-----PLRKLGTHCAVLVVNDVYVRRHLREFVTLLLRRLGFRR 255
            |......:||:|.:..|..|.:     ||  |.|.      ..:..|.:..:...::....|...
Human    79 LITGWDDVERLWKHLFEWELGVKPSDQPL--LATE------PSLNPRENREKMAEVMFENFGVPA 135

  Fly   256 CFLVQDSVASTFGAGIGYGCVVDIGAQKTSIACIEDGISQLDARVRLSYGGGDLDQVLLLLLRKC 320
            .:|...:|.:.:.:....|.|||.|...|....|.:|.|...|..:|...|.|:.::|:.||...
Human   136 FYLSDQAVLALYASACVTGLVVDSGDAVTCTVPIFEGYSLPHAVTKLHVAGRDITELLMQLLLAS 200

  Fly   321 G--FPYRECNVQESYVDAHLLDELKEKFCHLNASVCGAQEKHFNLRKHNGQWLRYTIQVGDEALM 383
            |  ||   |.     :|..|:|::|:|.|::      |.|....|.:...:.||
Human   201 GHTFP---CQ-----LDKGLVDDIKKKLCYV------ALEPEKELSRRPEEVLR----------- 240

  Fly   384 APLALFHTELLNITGRTKAVFTQQAVQDQYDCEDCFDAEYLKETGRKNGVRGGDILQLSTSAGYQ 448
                                        :|...|                  |:|:.|.     .
Human   241 ----------------------------EYKLPD------------------GNIISLG-----D 254

  Fly   449 PRPQLPVTADDEELIVVDQDETISNCQSQLGAQTAGGQMNSNGCYHNGQGLVLPLDQAIIQSINR 513
            |..|.|      |.:.|.|         |||:|:.|                  |...:..||.:
Human   255 PLHQAP------EALFVPQ---------QLGSQSPG------------------LSNMVSSSITK 286

  Fly   514 LSSYETKRKMFGSILLVGSSAKLPGLAAWLEQRISQQVQSEVNVLIKG-MDAGMVAWKGAAIMSV 577
            ..: :.::.:||.|:|.|.:....||...|.:.:.|....:..:.|.. .|.....|.||:|::.
Human   287 CDT-DIQKILFGEIVLSGGTTLFHGLDDRLLKELEQLASKDTPIKITAPPDRWFSTWIGASIVTS 350

  Fly   578 LESARELWISQNDWQRHGLRVLRER 602
            |.|.:::|::..|::..|..|::.|
Human   351 LSSFKQMWVTAADFKEFGTSVVQRR 375

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Arp8	NP_573251.1	NBD_sugar-kinase_HSP70_actin	202..603	CDD:302596	85/409 (21%)
ACTRT2	NP_536356.3	ACTIN	10..377	CDD:214592	110/539 (20%)
		NBD_sugar-kinase_HSP70_actin	11..377	CDD:302596	109/533 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5277
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810