Protein Alignment Arp8 and ACTL7B

DIOPT Version :9

• Sequence 1: NP_573251.1
• Gene: Arp8 / 32769
• FlyBaseID: FBgn0030877
• Length: 607
• Species: Drosophila melanogaster
• Sequence 2: NP_006677.1
• Gene: ACTL7B / 10880
• HGNCID: 162
• Length: 415
• Species: Homo sapiens
• Alignment Length: 627
• Identity: 108/627 - (17%)
• Similarity: 181/627 - (28%)
• Gaps: 272/627 - (43%)

  Fly    16 APPPIGL-----------PQPQA-------------QPLEAPKI--IVIHPGSQHLRIGRAADLN 54
            :|.|:|.           |.|.|             :|.:..||  ::|..|||:.:.|.|.:..
Human     6 SPMPLGTAQGDPGEAGTRPGPDASLRDTGAATQLKMKPRKVHKIKAVIIDLGSQYCKCGYAGEPR 70

  Fly    55 PLTLLHAVAYRRRPGASDRPH--------HDPL--LPPLDNVNS-NSGLMVEFEEQRLVVSRILQ 108
            |...:.:...:|.|.|:|...        |:.|  ..||..||. ..|::|:::
Human    71 PTYFISSTVGKRCPEAADAGDTRKWTLVGHELLNTEAPLKLVNPLKHGIVVDWD----------- 124

  Fly   109 HCVVDNKNRLRVATPPQQLAHFNRSSQAEKVPAPSGQMADEPWLDREAPVLFDDRILRLGAVDAR 173
             ||.|
Human   125 -CVQD------------------------------------------------------------ 128

  Fly   174 NYDIHFPIQRGELNVHNEKGGSLQASMQHLERIWSYALEERLKIPLRKLGTHCAVLVVNDVYVRR 238
                                            ||.|.....:||    |....||||.:......
Human   129 --------------------------------IWEYIFRTAMKI----LPEEHAVLVSDPPLSPS 157

  Fly   239 HLRE-FVTLLLRRLGFRRCFLVQDSVASTFGAGIGYGCVVDIGAQKTSIACIEDGISQLDARVRL 302
            ..|| :..|:....|.....:...|:.|.:..|...|.||:.|...:.:..|.:|........|.
Human   158 SNREKYAELMFETFGIPAMHVTSQSLLSIYSYGKTSGLVVESGHGVSHVVPISEGDVLPGLTSRA 222

  Fly   303 SYGGGDLDQVLLLLLRKCGFPYRECNVQESYVDAHLLDELKEKFCHLNASVCGAQEKHFNLRKHN 367
            .|.||||...|:.||.:.|..:.:.::       |:::.:|:|.|:  |:....:|
Human   223 DYAGGDLTNYLMQLLNEAGHAFTDDHL-------HIIEHIKKKCCY--AAFLPEEE--------- 269

  Fly   368 GQWLRYTIQVGDEALMAPLALFHTELLNITGRTKAVFTQQAVQDQYDCEDCFDAEYLKETGRKNG 432
                              |.|...||                          ..:|
Human   270 ------------------LGLVPEEL--------------------------RVDY--------- 281

  Fly   433 VRGGDILQLSTSAGYQPRPQLPVTADDEELIVVDQDETISNCQSQLGAQTAGGQMNSNGCYHNGQ 497
                               :||    |.:||.:.|:.  ..|...|...:..|.....
Human   282 -------------------ELP----DGKLITIGQER--FRCSEMLFQPSLAGSTQPG------- 314

  Fly   498 GLVLPLDQAIIQSINRLSSYETKRKMFGSILLVGSSAKLPGLAAWLEQRISQQVQSEVNVLIKGM 562
                 |.:.....:.|......|.:|..::||.|....|.|        ..::.|.|:::|..|
Human   315 -----LPELTAACLGRCQDTGFKEEMAANVLLCGGCTMLDG--------FPERFQRELSLLCPG- 365

  Fly   563 DAGMVA---------WKGAAIMSVLESARELWISQNDWQRHG 595
            |:..||         |.|.:|::.|::.::||:|:.:::..|
Human   366 DSPAVAAAPERKTSVWTGGSILASLQAFQQLWVSKEEFEERG 407

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Arp8	NP_573251.1	NBD_sugar-kinase_HSP70_actin	202..603	CDD:302596	77/404 (19%)
ACTL7B	NP_006677.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..31		6/24 (25%)
		NBD_sugar-kinase_HSP70_actin	51..415	CDD:327376	99/582 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5277
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810