Protein Alignment Arp8 and ACTR2

DIOPT Version :9

• Sequence 1: NP_573251.1
• Gene: Arp8 / 32769
• FlyBaseID: FBgn0030877
• Length: 607
• Species: Drosophila melanogaster
• Sequence 2: NP_001005386.1
• Gene: ACTR2 / 10097
• HGNCID: 169
• Length: 399
• Species: Homo sapiens
• Alignment Length: 495
• Identity: 90/495 - (18%)
• Similarity: 162/495 - (32%)
• Gaps: 184/495 - (37%)

  Fly   157 PVLFDDRILR----LGAVDARN------------------YDIHFPIQRGELNVHNEKGGSLQAS 199
            |.|....|:|    :|.::.:|                  .::::|::.|.:...::
Human    33 PALVGRPIIRSTTKVGNIEIKNNKKMDLMVGDEASELRSMLEVNYPMENGIVRNWDD-------- 89

  Fly   200 MQHLERIWSYAL-EERLKIPLRKLGTHCAVLVVN-DVYVRRHLREFVTLLLRRLGFRRCFLVQDS 262
            |:||   |.|.. .|:|.|..|    :|.:|:.. .:...::..:.|.::.....|...::...:
Human    90 MKHL---WDYTFGPEKLNIDTR----NCKILLTEPPMNPTKNREKIVEVMFETYQFSGVYVAIQA 147

  Fly   263 VASTFGAGIGYGCVVDIGAQKTSIACIEDGISQLDARVRLSYGGGDLDQVLLLLLRKCGFPYREC 327
            |.:.:..|:..|.|||.|...|.|..:.:|.|......||...|.|:.:.|:.||...|:.:...
Human   148 VLTLYAQGLLTGVVVDSGDGVTHICPVYEGFSLPHLTRRLDIAGRDITRYLIKLLLLRGYAFNHS 212

  Fly   328 NVQESYVDAHLLDELKEKFCHLNASVCGAQEKHFNLRKHNGQWLRYT-------------IQVGD 379
                  .|...:..:|||.|::.          :|:.:.....|..|             |:||.
Human   213 ------ADFETVRMIKEKLCYVG----------YNIEQEQKLALETTVLVESYTLPDGRIIKVGG 261

  Fly   380 EALMAPLALFHTELLNITGRTKAVFTQQAVQDQYDCEDCFDAEYLKETGRKNGVRGGDILQLSTS 444
            |...||.|||...|:|:.|...|             |..|           |.::..||
Human   262 ERFEAPEALFQPHLINVEGVGVA-------------ELLF-----------NTIQAADI------ 296

  Fly   445 AGYQPRPQLPVTADDEELIVVDQDETISNCQSQLGAQTAGGQMNSNGCYHNGQGLVLPLDQAIIQ 509
                                                                             
Human   297 ----------------------------------------------------------------- 296

  Fly   510 SINRLSSYETKRKMFGSILLVGSSAKLPGLAAWLEQRISQ-----QVQSEVNVLIK--------G 561
                    :|:.:.:..|:|.|.|...|||.:.||:.:.|     .::.:|..|.|        .
Human   297 --------DTRSEFYKHIVLSGGSTMYPGLPSRLERELKQLYLERVLKGDVEKLSKFKIRIEDPP 353

  Fly   562 MDAGMVAWKGAAIMSVLESARELWISQNDWQRHGLRVLRE 601
            ....||...||.:..:::.....|:::.::|..|:|||.:
Human   354 RRKHMVFLGGAVLADIMKDKDNFWMTRQEYQEKGVRVLEK 393

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Arp8	NP_573251.1	NBD_sugar-kinase_HSP70_actin	202..603	CDD:302596	81/428 (19%)
ACTR2	NP_001005386.1	ACTIN	6..393	CDD:214592	90/493 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5277
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810