DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spt7 and supt7l

DIOPT Version :9

Sequence 1:	NP_573248.2	Gene:	Spt7 / 32766	FlyBaseID:	FBgn0030874	Length:	359	Species:	Drosophila melanogaster
Sequence 2:	NP_001013310.1	Gene:	supt7l / 503605	ZFINID:	ZDB-GENE-050227-17	Length:	414	Species:	Danio rerio

Alignment Length:	393	Identity:	82/393 - (20%)
Similarity:	141/393 - (35%)	Gaps:	88/393 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 HWGSLP-AEDDGGQLTPDKYVPTAAKKLKLDEIRQ--RGDP---QPQEKHHK----LELRS---A 56
            :||.|| |....|:.:.|         |...|.||  ..||   ||..:..:    |::.|   :
Zfish     4 YWGELPVASASSGRSSFD---------LLQREFRQVEMQDPPLHQPSAQRPRPTTMLDIPSEPCS 59

  Fly    57 LVTQTIEVMKQTEVLQSLIETYSNKNGSSNYLLNPCLMIPEVDFPPENAAELVGSQKFQKPIWFT 121
            |...|:::.:....|:.||.  :.:.|....   |.|:..:..|.||....|       .|...|
Zfish    60 LTIHTVQLSQHARRLRGLIA--AAQQGQQPL---PTLLEGQSAFKPEEGDAL-------PPRPPT 112

  Fly   122 PTV-----------------------DTAYSRGDPEAYPEIPSSACRQAMRKVMCGMLRLAGFTD 163
            |||                       ::.:.:|..|...|:...:|||.:.:.:..:|...||..
Zfish   113 PTVPDDLLPLDSKAPRLPFQLRHSDPESDFYKGKGEPVTELSWPSCRQLLYQSVATVLAHIGFES 177

  Fly   164 CSESAVQLLTDATEEFLRSFIGEYRGYYDSQPRLQNSTVLQLVPLERAHFAQTGTSL-------T 221
            .:||.::.|||...|.........|...|.: ..|.||....|..:..|....|:.|       .
Zfish   178 ANESVLETLTDLVHEHYLRLTKLLRVAVDRE-ACQGSTAFPDVLEQVFHELGIGSILALQRFWQV 241

  Fly   222 QVHNYYKHKVLARNRAEIAEFNSVLQEYDKLMKESQSSMQKQHNEFNGHDFLNILDNSATGSSQS 286
            ::.:|  |..:.:...|::|...:|...:|.:::|:....|:.         .:.|.:...|.:.
Zfish   242 RIKDY--HSYMLQVSKELSEEYDILVNPEKALEDSKPLKVKEE---------PVSDIAFPLSEEP 295

  Fly   287 IGGMAMGDMLQDL------------GGSTGSSGTVSSQQMLYGLLDGQISSNTSNMTGTSGNGST 339
            ...:|.||....:            |.|..:||...:...|:.|...::....|.....||:|..
Zfish   296 EADLASGDQALPIGVLGTSSERLEEGHSPHASGAAGNSPPLWHLAQVKMEPQDSEEGQVSGHGVL 360

  Fly   340 GGN 342
            |.:
Zfish   361 GSD 363

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spt7	NP_573248.2	None
supt7l	NP_001013310.1	TAF9	155..229	CDD:304618	19/74 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28IGQ
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR28598
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	3	2.960