DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15814 and rnf121

DIOPT Version :9

Sequence 1:	NP_573247.2	Gene:	CG15814 / 32765	FlyBaseID:	FBgn0030873	Length:	321	Species:	Drosophila melanogaster
Sequence 2:	NP_001295485.1	Gene:	rnf121 / 606559	ZFINID:	ZDB-GENE-050809-3	Length:	331	Species:	Danio rerio

Alignment Length:	320	Identity:	186/320 - (58%)
Similarity:	243/320 - (75%)	Gaps:	6/320 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 HQEHMDLHEPVDLNKSLDEMTPEERMRAQHQLMVEKHRGHDAMHSEMVIILFVTLVIAQIILVEW 66
            |..|.|  ..:||::    ::|||:.|..|..:..||:||:|||:|||:||.||||:||:.||:|
Zfish    18 HGHHED--GKIDLSR----LSPEEKWRLDHAKLHAKHKGHEAMHAEMVLILIVTLVVAQLALVQW 76

  Fly    67 KKRHYRSYAFVTLLAMWLIPLIISCSFGWLRFIIIWLVFTCITALVMRRAISKPIQGTTPRLVYK 131
            |:||.:||..|||..||:|||..:....|.||:::|..|:.|||.|..||..||:..||||||||
Zfish    77 KQRHQKSYNMVTLFQMWVIPLYFTSKLHWWRFMVVWFTFSIITAFVTFRATRKPLACTTPRLVYK 141

  Fly   132 WFYFIYKLSYGLGLVGYLVIIAAFLGMNYMFSQPPNTWMDVGLMFCFYGLYIGVLGRDISEICSD 196
            ||...||::||.|:|||.:::....|:|.:|...|:..||:|:...|||||.||||||.:|||:|
Zfish   142 WFLLFYKINYGTGIVGYAIVMLTLFGINLLFGIKPDDCMDLGVSLLFYGLYFGVLGRDFAEICAD 206

  Fly   197 KMAAAIGYYTPQGIPTRHLDQNVCAVCGNQLLVSEKEEGVIENTYKLSCNHVFHEFCIRGWCIVG 261
            .||:.|||||..|:||:||..::|||||...||...:||:|||||:|:|||||||||||||||||
Zfish   207 VMASTIGYYTESGMPTKHLSDSICAVCGQTTLVDANQEGIIENTYRLTCNHVFHEFCIRGWCIVG 271

  Fly   262 KKQTCPYCKEKVDLQKMFRNPWEKPHVLYGRLLDWIRWLVAWQPLIFFIVQGINWMLGLE 321
            ||||||||||||||::|||||||:||::||:||||:|:||||||:|..:||.||::||||
Zfish   272 KKQTCPYCKEKVDLKRMFRNPWERPHMMYGQLLDWLRYLVAWQPIIIGLVQLINYILGLE 331

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15814	NP_573247.2	zf-RING_2	218..270	CDD:290367	39/51 (76%)
rnf121	NP_001295485.1	RING	230..283	CDD:238093	42/52 (81%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170580528
Domainoid	1	1.000	240	1.000	Domainoid score	I2218
eggNOG	1	0.900	-	-		E1_KOG1734
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H10132
Inparanoid	1	1.050	421	1.000	Inparanoid score	I1762
OMA	1	1.010	-	-		QHG55575
OrthoDB	1	1.010	-	-		D1167893at2759
OrthoFinder	1	1.000	-	-		FOG0005045
OrthoInspector	1	1.000	-	-		otm26161
orthoMCL	1	0.900	-	-		OOG6_104557
Panther	1	1.100	-	-	LDO	PTHR13407
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2764
SonicParanoid	1	1.000	-	-		X3568
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.800