DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15814 and rnf175

DIOPT Version :9

Sequence 1:	NP_573247.2	Gene:	CG15814 / 32765	FlyBaseID:	FBgn0030873	Length:	321	Species:	Drosophila melanogaster
Sequence 2:	NP_001315272.1	Gene:	rnf175 / 393278	ZFINID:	ZDB-GENE-040426-1104	Length:	313	Species:	Danio rerio

Alignment Length:	312	Identity:	181/312 - (58%)
Similarity:	231/312 - (74%)	Gaps:	3/312 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 EPVDLNKSLDEMTPEERMRAQHQLMVEKHRGHDAMHSEMVIILFVTLVIAQIILVEWKKRHYRSY 74
            :|.|   .|.:|:..|..:.||:.:..|||||:|||:|||:||..|||:|||:||:||:||.|||
Zfish     5 QPQD---DLLKMSHRESWKMQHERLHVKHRGHEAMHAEMVLILIATLVVAQIVLVQWKQRHCRSY 66

  Fly    75 AFVTLLAMWLIPLIISCSFGWLRFIIIWLVFTCITALVMRRAISKPIQGTTPRLVYKWFYFIYKL 139
            ..||||.||::||..:....|.||:..|.:|:.||:.|:.||..||:...|||:|||||..||||
Zfish    67 NMVTLLQMWVVPLYFTIKLYWWRFLSTWGMFSVITSYVIFRATRKPLSCRTPRMVYKWFLLIYKL 131

  Fly   140 SYGLGLVGYLVIIAAFLGMNYMFSQPPNTWMDVGLMFCFYGLYIGVLGRDISEICSDKMAAAIGY 204
            ||.:|::|||.|:....|.|..|.......||||::..|||||.||:|||.:|||||.||:.|||
Zfish   132 SYAVGVIGYLAIMFTMFGFNVFFRIKAEDSMDVGVIMLFYGLYYGVMGRDFAEICSDYMASTIGY 196

  Fly   205 YTPQGIPTRHLDQNVCAVCGNQLLVSEKEEGVIENTYKLSCNHVFHEFCIRGWCIVGKKQTCPYC 269
            |....:|:|:|:.:||||||.::.|...|||:||:||:|||||.|||||||||||||||||||||
Zfish   197 YNMGDMPSRNLNNDVCAVCGQKIFVDVDEEGIIEDTYQLSCNHTFHEFCIRGWCIVGKKQTCPYC 261

  Fly   270 KEKVDLQKMFRNPWEKPHVLYGRLLDWIRWLVAWQPLIFFIVQGINWMLGLE 321
            .|||||::|..||||:.|||||:||||:|:||||||:|..||.|||:.||||
Zfish   262 NEKVDLKRMMNNPWERTHVLYGQLLDWLRYLVAWQPIIIGIVHGINFSLGLE 313

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15814	NP_573247.2	zf-RING_2	218..270	CDD:290367	39/51 (76%)
rnf175	NP_001315272.1	zf-RING_2	210..261	CDD:290367	38/50 (76%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170580527
Domainoid	1	1.000	240	1.000	Domainoid score	I2218
eggNOG	1	0.900	-	-		E1_KOG1734
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	421	1.000	Inparanoid score	I1762
OMA	1	1.010	-	-		QHG55575
OrthoDB	1	1.010	-	-		D1167893at2759
OrthoFinder	1	1.000	-	-		FOG0005045
OrthoInspector	1	1.000	-	-		otm26161
orthoMCL	1	0.900	-	-		OOG6_104557
Panther	1	1.100	-	-	O	PTHR13407
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2764
SonicParanoid	1	1.000	-	-		X3568
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	15	14.800