DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15814 and Rnf121

DIOPT Version :9

Sequence 1:	NP_573247.2	Gene:	CG15814 / 32765	FlyBaseID:	FBgn0030873	Length:	321	Species:	Drosophila melanogaster
Sequence 2:	NP_001101010.1	Gene:	Rnf121 / 308871	RGDID:	1307857	Length:	327	Species:	Rattus norvegicus

Alignment Length:	312	Identity:	184/312 - (58%)
Similarity:	241/312 - (77%)	Gaps:	4/312 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 EPVDLNKSLDEMTPEERMRAQHQLMVEKHRGHDAMHSEMVIILFVTLVIAQIILVEWKKRHYRSY 74
            :.||::    :::|||:.|.:|..|..|||||:|||:|||:||..|||:||::||:||:||.|||
  Rat    20 DEVDMS----DLSPEEQWRVEHARMHAKHRGHEAMHAEMVLILIATLVVAQLLLVQWKQRHPRSY 80

  Fly    75 AFVTLLAMWLIPLIISCSFGWLRFIIIWLVFTCITALVMRRAISKPIQGTTPRLVYKWFYFIYKL 139
            ..|||..||::||..:....|.||::||:.|:.:||.|..||..||:..||||||||||..|||:
  Rat    81 NMVTLFQMWVVPLYFTVKLHWWRFLVIWIFFSAVTAFVTFRATRKPLVQTTPRLVYKWFLLIYKI 145

  Fly   140 SYGLGLVGYLVIIAAFLGMNYMFSQPPNTWMDVGLMFCFYGLYIGVLGRDISEICSDKMAAAIGY 204
            ||..|:|||:.::....|:|.:|...|...||.|:...|||||.|||.||.:|:|:|.||:.||:
  Rat   146 SYATGIVGYMAVMFTLFGLNLLFKIKPEDAMDFGISLLFYGLYYGVLERDFAEMCADYMASTIGF 210

  Fly   205 YTPQGIPTRHLDQNVCAVCGNQLLVSEKEEGVIENTYKLSCNHVFHEFCIRGWCIVGKKQTCPYC 269
            |:..|:||:||..:||||||.|:.|...|||:|||||:|||||||||||||||||||||||||||
  Rat   211 YSESGMPTKHLSDSVCAVCGQQIFVDVNEEGIIENTYRLSCNHVFHEFCIRGWCIVGKKQTCPYC 275

  Fly   270 KEKVDLQKMFRNPWEKPHVLYGRLLDWIRWLVAWQPLIFFIVQGINWMLGLE 321
            ||||||::||.||||:|||:||:||||:|:||||||:|..:||||:::||||
  Rat   276 KEKVDLKRMFSNPWERPHVMYGQLLDWLRYLVAWQPVIIGLVQGISYILGLE 327

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15814	NP_573247.2	zf-RING_2	218..270	CDD:290367	42/51 (82%)
Rnf121	NP_001101010.1	RING-H2_RNF121_like	224..278	CDD:319389	44/53 (83%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166340714
Domainoid	1	1.000	234	1.000	Domainoid score	I2304
eggNOG	1	0.900	-	-		E1_KOG1734
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H10132
Inparanoid	1	1.050	422	1.000	Inparanoid score	I1726
OMA	1	1.010	-	-		QHG55575
OrthoDB	1	1.010	-	-		D1167893at2759
OrthoFinder	1	1.000	-	-		FOG0005045
OrthoInspector	1	1.000	-	-		oto97432
orthoMCL	1	0.900	-	-		OOG6_104557
Panther	1	1.100	-	-	LDO	PTHR13407
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3568
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770