Protein Alignment CG15814 and RNF175

DIOPT Version :10

• Sequence 1: NP_573247.2
• Gene: CG15814 / 32765
• FlyBaseID: FBgn0030873
• Length: 321
• Species: Drosophila melanogaster
• Sequence 2: NP_775933.2
• Gene: RNF175 / 285533
• HGNCID: 27735
• Length: 328
• Species: Homo sapiens
• Alignment Length: 302
• Identity: 174/302 - (57%)
• Similarity: 224/302 - (74%)
• Gaps: 0/302 - (0%)

  Fly    20 EMTPEERMRAQHQLMVEKHRGHDAMHSEMVIILFVTLVIAQIILVEWKKRHYRSYAFVTLLAMWL 84
            :::.|:....|.:.|.:.|||||:||.||::|....||||||:||:|::||.|||..||||.||:
Human    27 KLSAEDTWNLQQERMYKMHRGHDSMHVEMILIFLCVLVIAQIVLVQWRQRHGRSYNLVTLLQMWV 91

  Fly    85 IPLIISCSFGWLRFIIIWLVFTCITALVMRRAISKPIQGTTPRLVYKWFYFIYKLSYGLGLVGYL 149
            :||..:....|.||:.:|.:|:.||:.::.||..||:.|.|||||||||..||||||..|:||||
Human    92 VPLYFTIKLYWWRFLSMWGMFSVITSYILFRATRKPLSGRTPRLVYKWFLLIYKLSYAFGVVGYL 156

  Fly   150 VIIAAFLGMNYMFSQPPNTWMDVGLMFCFYGLYIGVLGRDISEICSDKMAAAIGYYTPQGIPTRH 214
            .|:....|.|..|.......||.|::..|||||.||:|||.:|||||.||:.||:|:...:|||.
Human   157 AIMFTMCGFNLFFKIKARDSMDFGIVSLFYGLYYGVMGRDFAEICSDYMASTIGFYSVSRLPTRS 221

  Fly   215 LDQNVCAVCGNQLLVSEKEEGVIENTYKLSCNHVFHEFCIRGWCIVGKKQTCPYCKEKVDLQKMF 279
            |..|:|||||.:::|...|||:|||||:|||||||||||||||||||||||||||||||||::|.
Human   222 LSDNICAVCGQKIIVELDEEGLIENTYQLSCNHVFHEFCIRGWCIVGKKQTCPYCKEKVDLKRMI 286

  Fly   280 RNPWEKPHVLYGRLLDWIRWLVAWQPLIFFIVQGINWMLGLE 321
            .||||:.|.|||::|||:|:||||||::..|||||.:.||||
Human   287 SNPWERTHFLYGQILDWLRYLVAWQPVVIGIVQGIIYSLGLE 328

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15814	NP_573247.2	RING-H2_RNF121-like	218..272	CDD:438138	43/53 (81%)
RNF175	NP_775933.2	RING-H2_RNF121-like	225..279	CDD:438138	43/53 (81%)