Protein Alignment Ucp4A and SLC25A14

DIOPT Version :10

• Sequence 1: NP_573246.1
• Gene: Ucp4A / 32764
• FlyBaseID: FBgn0030872
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: NP_001269126.1
• Gene: SLC25A14 / 9016
• HGNCID: 10984
• Length: 353
• Species: Homo sapiens
• Alignment Length: 332
• Identity: 108/332 - (32%)
• Similarity: 178/332 - (53%)
• Gaps: 62/332 - (18%)

  Fly    44 YIVSVVAASIAELATYPLDLTKTRLQIQGEGAAHSAGKSNMQYRGMVATAFGIAREEGALKLWQG 108
            ::...:|:.:||..|:|:||||||||:||:..  .|....::||||....|.|.:|||.|.|:.|
Human    41 FVYGGLASIVAEFGTFPVDLTKTRLQVQGQSI--DARFKEIKYRGMFHALFRICKEEGVLALYSG 103

  Fly   109 VTPALYRHVVYSGVRICSYDLMRKEFTQN-GTQALPVWKSALCGVTAGAVAQWLASPADLVKVQI 172
            :.|||.|...|..::|..|..:::.|.:. ..:.|.:  :.:|||.:|.::..:|:|.|::|:::
Human   104 IAPALLRQASYGTIKIGIYQSLKRLFVERLEDETLLI--NMICGVVSGVISSTIANPTDVLKIRM 166

  Fly   173 QMEG---RRRLMGEPPRVHSAGHAFRQIVQRGGIKGLWK-------------------------- 208
            |.:|   :..::|          :|..|.|:.|.:|||:
Human   167 QAQGSLFQGSMIG----------SFIDIYQQEGTRGLWRCLCSKAVTGCVLWLMPVIPALWEANA 221

  Fly   209 -----GSIPNVQRAALVNLGDLTTYD-TIKHLIMNRLQMPDCHTVHVLASVCAGFVAAIMGTPAD 267
                 |.:|..||||:|...:|..|| |.||||::.: |.|....|.::|...|...|:...|.|
Human   222 GGSLEGVVPTAQRAAIVVGVELPVYDITKKHLILSGM-MGDTILTHFVSSFTCGLAGALASNPVD 285

  Fly   268 VVKTRIMNQPTDENGRGL-----LYRGSVDCLRQTVSKEGFVALYKGFLPCWIRMAPWSLTFWLS 327
            ||:||:|||      |.:     ||:|:||.:.:....|||.||||||.|.|:|:.||::.|:::
Human   286 VVRTRMMNQ------RAIVGHVDLYKGTVDGILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFIT 344

  Fly   328 FEQIRKM 334
            :||::::
Human   345 YEQLKRL 351

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ucp4A	NP_573246.1	Mito_carr	39..138	CDD:395101	36/94 (38%)
		Mito_carr	142..239	CDD:395101	34/131 (26%)
		Mito_carr	248..336	CDD:395101	36/92 (39%)
SLC25A14	NP_001269126.1	Mito_carr	37..133	CDD:395101	36/93 (39%)
		Mito_carr	134..254	CDD:395101	32/131 (24%)
		Mito_carr	262..351	CDD:395101	36/94 (38%)