Protein Alignment Ucp4A and SLC25A11

DIOPT Version :9

• Sequence 1: NP_001188664.1
• Gene: Ucp4A / 32764
• FlyBaseID: FBgn0030872
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: XP_024306762.1
• Gene: SLC25A11 / 8402
• HGNCID: 10981
• Length: 342
• Species: Homo sapiens
• Alignment Length: 358
• Identity: 99/358 - (27%)
• Similarity: 163/358 - (45%)
• Gaps: 61/358 - (17%)

  Fly    12 VASSTSSNPAPSSGRHQLRP--VKFDYADSFACTYIVSVVAASIAELATYPLDLTKTRLQIQGEG 74
            :|::.|:......|:.:..|  |||          :...:|...|.:...||||.|.|:|:.|||
Human     1 MAATASAGAGGIDGKPRTSPKSVKF----------LFGGLAGMGATVFVQPLDLVKNRMQLSGEG 55

  Fly    75 AAHSAGKSNMQ----------YRGMVATAFGIAREEGALKLWQG--------VTP-------ALY 114
            |.....|::..          .||:....:|: |.||  :||.|        :||       .|.
Human    56 AKTREYKTSFHALTSILKAEGLRGIYTGYWGL-RMEG--RLWVGSSRPWPDMLTPLLLRLSAGLL 117

  Fly   115 RHVVYSGVRICSYDLMRKEFTQNGTQALP--VWKSALCGVTAGAVAQWLASPADLVKVQIQMEGR 177
            |...|:..|:..|.::.:..|  |....|  ....|:.|:||||...::.:||::..:::..:|
Human   118 RQATYTTTRLGIYTVLFERLT--GADGTPPGFLLKAVIGMTAGATGAFVGTPAEVALIRMTADG- 179

  Fly   178 RRLMGEPPRVH-SAGHAFRQIVQRGGIKGLWKGSIPNVQRAALVNLGDLTTYDTIKHLIMNRLQM 241
             ||..:..|.: :..:|..:|.:..|:..||:|.||.:.||.:||...|.:|...|..:::....
Human   180 -RLPADQRRGYKNVFNALIRITREEGVLTLWRGCIPTMARAVVVNAAQLASYSQSKQFLLDSGYF 243

  Fly   242 PDCHTVHVLASVCAGFVAAIMGTPADVVKTRIMN------QPTDENGRGLLYRGSVDCLRQTVSK 300
            .|....|..||:.:|.|......|.|:.||||.|      :|..:||        :|.|.:.|..
Human   244 SDNILCHFCASMISGLVTTAASMPVDIAKTRIQNMRMIDGKPEYKNG--------LDVLFKVVRY 300

  Fly   301 EGFVALYKGFLPCWIRMAPWSLTFWLSFEQIRK 333
            |||.:|:|||.|.:.|:.|.::..::..||:.|
Human   301 EGFFSLWKGFTPYYARLGPHTVLTFIFLEQMNK 333

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ucp4A	NP_001188664.1	PTZ00169	39..335	CDD:240302	92/329 (28%)
		Mito_carr	39..138	CDD:278578	31/123 (25%)
		Mito_carr	142..239	CDD:278578	28/99 (28%)
		Mito_carr	248..336	CDD:278578	31/92 (34%)
SLC25A11	XP_024306762.1	Mito_carr	24..>85	CDD:278578	18/70 (26%)
		Mito_carr	144..241	CDD:278578	28/98 (29%)
		Mito_carr	243..337	CDD:278578	32/99 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0759
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810