Protein Alignment Ucp4A and UCP1

DIOPT Version :10

• Sequence 1: NP_573246.1
• Gene: Ucp4A / 32764
• FlyBaseID: FBgn0030872
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: NP_068605.1
• Gene: UCP1 / 7350
• HGNCID: 12517
• Length: 307
• Species: Homo sapiens
• Alignment Length: 291
• Identity: 96/291 - (32%)
• Similarity: 164/291 - (56%)
• Gaps: 14/291 - (4%)

  Fly    49 VAASIAELATYPLDLTKTRLQIQGEGAAHSAGKSNMQYRGMVATAFGIAREEGALKLWQGVTPAL 113
            :||.:|::.|:|||..|.|||:|||....|.    ::|:|::.|...:.:.||.:||:.|:...|
Human    22 IAACLADVITFPLDTAKVRLQVQGECPTSSV----IRYKGVLGTITAVVKTEGRMKLYSGLPAGL 82

  Fly   114 YRHVVYSGVRICSYDLMRKEFTQNGTQALP-VWKSALCGVTAGAVAQWLASPADLVKVQIQMEGR 177
            .|.:..:.:||..||.: :||...|.:..| :....|.|:|.|.||.::..|.::|||::|.:.
Human    83 QRQISSASLRIGLYDTV-QEFLTAGKETAPSLGSKILAGLTTGGVAVFIGQPTEVVKVRLQAQS- 145

  Fly   178 RRLMGEPPRVHSAGHAFRQIVQRGGIKGLWKGSIPNVQRAALVNLGDLTTYDTIKHLIMNRLQMP 242
             .|.|..||.....:|:|.|....|:.|||||:.||:.|:.::|..:|.|||.:|...:....:.
Human   146 -HLHGIKPRYTGTYNAYRIIATTEGLTGLWKGTTPNLMRSVIINCTELVTYDLMKEAFVKNNILA 209

  Fly   243 DCHTVHVLASVCAGFVAAIMGTPADVVKTRIMNQPTDENGRGLLYRGSVDCLRQTVSKEGFVALY 307
            |....|:::::.|||.|..|.:|.||||||.:|.|..:      |:...:|..:..:.||..|.:
Human   210 DDVPCHLVSALIAGFCATAMSSPVDVVKTRFINSPPGQ------YKSVPNCAMKVFTNEGPTAFF 268

  Fly   308 KGFLPCWIRMAPWSLTFWLSFEQIRKMIGAS 338
            ||.:|.::|:..|::..::.|||:::.:..|
Human   269 KGLVPSFLRLGSWNVIMFVCFEQLKRELSKS 299

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ucp4A	NP_573246.1	Mito_carr	39..138	CDD:395101	31/88 (35%)
		Mito_carr	142..239	CDD:395101	34/97 (35%)
		Mito_carr	248..336	CDD:395101	28/87 (32%)
UCP1	NP_068605.1	Mito_carr	10..104	CDD:395101	31/86 (36%)
		Solcar 1	11..102		29/84 (35%)
		Mito_carr	111..206	CDD:395101	34/96 (35%)
		Solcar 2	111..201		34/91 (37%)
		Solcar 3	210..295		29/90 (32%)
		Mito_carr	215..300	CDD:395101	29/91 (32%)