Protein Alignment Ucp4A and Slc25a35

DIOPT Version :10

• Sequence 1: NP_573246.1
• Gene: Ucp4A / 32764
• FlyBaseID: FBgn0030872
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: NP_082324.1
• Gene: Slc25a35 / 71998
• MGIID: 1919248
• Length: 300
• Species: Mus musculus
• Alignment Length: 488
• Identity: 95/488 - (19%)
• Similarity: 158/488 - (32%)
• Gaps: 176/488 - (36%)

  Fly    39 NKREETILKRRNVPQTTESTDEEDYTLQSNLKKLVEK-AGNSS--------------------DK 82
            |......:..:|.|    |.|.|...|:::...|:.| :|::|                    ||
Mouse   471 NAARPEYIASKNSP----SADSEQVVLRNDQDTLLAKWSGSNSRSSLHVDWHEEEWEKVWGNVDK 531

  Fly    83 EGQLAAVQAARRLLSSDRNPPINNLIDSGILPILVNCLEQDDNQVLQFEAAWA------LTNIAS 141
            ..: ..:|...:||..:|....::          .:..:.|.......:..|:      ||.:..
Mouse   532 SLE-CIIQRVDKLLQRERLHSSSS----------EDMFQSDQQGGTSKKGEWSEALYPLLTTLTE 585

  Fly   142 GTAAQTNQVVRAGAVPLFLRLLNSPAPNV--------------CEQAVWAL--GNIIGDGPSLRD 190
            ..|..:::..::   .:|| |:...||.:              | |.:.||  |.||.....|||
Mouse   586 CVAMMSDKAKKS---MVFL-LMQDSAPTIAMDLSLQYRRDVVFC-QTLTALICGFIIKLRNCLRD 645

  Fly   191 -------YVI-KLGVVQPLLSFIQPE--------IPIPFLRNVTWVIVNLCRNKDPPPPAATILE 239
                   |.| .|...:.|||....|        |.|..|||||:.:........|        :
Mouse   646 DGFLRQLYTIGLLAQFECLLSTYGEELAMLEDMSIGIMDLRNVTFKVTQAISTSSP--------D 702

  Fly   240 ILPALNMLIHHTDINILVDTVWALSYLTDGGNEQIQL----------VIDSGVVPKLIPLLSHVE 294
            :||                   .::...||.|.:|.|          .|.:|::.::.|:|.:|.
Mouse   703 MLP-------------------VITGNRDGFNVRIPLPGSMFDALPREIQNGMLLRVQPVLFNVG 748

  Fly   295 VKVQTAALRAVGNI-------------VTGSDDQTQVVLNCDALSH------FPKLL------TH 334
            :..|.......|:.             :.....|.:.||..|.|.|      .|:||      .|
Mouse   749 INEQQTLAEKFGDTSLQELINVESLARLNSYYQQFKEVLPDDCLPHSRSQTCLPELLRFLGQNVH 813

  Fly   335 SKDKIRKEAVWFLSNI------------------TAGNQSQVQAVI---DAGLLPKVIENLKHGD 378
            ::.....:.:|..:.|                  ||.:.:..|.:|   :.|:.|:|.
Mouse   814 ARKNKNVDILWQAAEICRRLNGVRFTSCKSAKDRTAMSVTLEQCLILQHEHGMAPQVF------- 871

  Fly   379 FHTQKEAAWAISNLTISGNREQVAQLINDGAVP 411
              ||     |:..:...|.||.|.|....|.:|
Mouse   872 --TQ-----ALDCMRSIGTREGVTQKNLSGLLP 897

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ucp4A	NP_573246.1	Mito_carr	39..138	CDD:395101	20/125 (16%)
		Mito_carr	142..239	CDD:395101	31/128 (24%)
		Mito_carr	248..336	CDD:395101	22/122 (18%)
Slc25a35	NP_082324.1	Solcar 1	1..90
		Mito_carr	2..84	CDD:395101
		Mito_carr	98..195	CDD:395101
		Solcar 2	100..193
		Solcar 3	203..294
		Mito_carr	209..298	CDD:395101