Protein Alignment Ucp4A and SLC25A35

DIOPT Version :10

• Sequence 1: NP_573246.1
• Gene: Ucp4A / 32764
• FlyBaseID: FBgn0030872
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: NP_001307799.1
• Gene: SLC25A35 / 399512
• HGNCID: 31921
• Length: 300
• Species: Homo sapiens
• Alignment Length: 307
• Identity: 93/307 - (30%)
• Similarity: 154/307 - (50%)
• Gaps: 31/307 - (10%)

  Fly    44 YIVSVVAASIAELATYPLDLTKTRLQIQGEGAAHSAGKSNMQYRGMVATAFGIAREEGALKLWQG 108
            :::|.:||..|.:.|.||::.|||:|:|||  ..:.|.....||.:......|.:.:|...|.:|
Human     3 FLMSGLAACGACVFTNPLEVVKTRMQLQGE--LQAPGTYQRHYRNVFHAFITIGKVDGLAALQKG 65

  Fly   109 VTPALYRHVVYSGVRICSYDLMRKE---FTQNGTQALPVWKSALCGVTAGAVAQWLASPADLVKV 170
            :.|||....:.:|:|:.:|.|....   .|..||.: |. :||..|..||.:..:|.||..:||.
Human    66 LAPALLYQFLMNGIRLGTYGLAEAGGYLHTAEGTHS-PA-RSAAAGAMAGVMGAYLGSPIYMVKT 128

  Fly   171 QIQMEGRRRLMGEPPRVHSAGHAFR---------QIVQRGGIKGLWKGSIPNVQRAALVNLGDLT 226
            .:|.:....:        :.||.::         :|.|:.|:.|||:|::..:.|..:.:...|.
Human   129 HLQAQAASEI--------AVGHQYKHQGMFQALTEIGQKHGLVGLWRGALGGLPRVIVGSSTQLC 185

  Fly   227 TYDTIKHLIMN-RLQMPDCHTVHVLASVCAGFVAAIMGTPADVVKTRIMNQPTDENGRGLLYRGS 290
            |:.:.|.|:.. .:..|....:.::|::.:|....:...|.||..||:.|||||..|:||:|||.
Human   186 TFSSTKDLLSQWEIFPPQSWKLALVAAMMSGIAVVLAMAPFDVACTRLYNQPTDAQGKGLMYRGI 250

  Fly   291 VDCLRQTVSKEGFVALYKGFLPCWIRMAP---WSLTFWLSFEQIRKM 334
            :|.|.||...||...:|||....:.|:.|   .||.||   :|:|.:
Human   251 LDALLQTARTEGIFGMYKGIGASYFRLGPHTILSLFFW---DQLRSL 294

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ucp4A	NP_573246.1	Mito_carr	39..138	CDD:395101	29/96 (30%)
		Mito_carr	142..239	CDD:395101	26/106 (25%)
		Mito_carr	248..336	CDD:395101	35/90 (39%)
SLC25A35	NP_001307799.1	Solcar 1	1..90		28/88 (32%)
		Mito_carr	2..84	CDD:395101	26/82 (32%)
		Solcar 2	100..193		25/102 (25%)
		PTZ00169	<122..294	CDD:240302	54/182 (30%)
		Solcar 3	203..294		35/93 (38%)
		Mito_carr	209..298	CDD:395101	35/89 (39%)