DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ucp4A and CG4995

DIOPT Version :9

Sequence 1:	NP_001188664.1	Gene:	Ucp4A / 32764	FlyBaseID:	FBgn0030872	Length:	340	Species:	Drosophila melanogaster
Sequence 2:	NP_609380.1	Gene:	CG4995 / 34390	FlyBaseID:	FBgn0032219	Length:	399	Species:	Drosophila melanogaster

Alignment Length:	191	Identity:	52/191 - (27%)
Similarity:	84/191 - (43%)	Gaps:	11/191 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly   149 LCGVTAGAVAQWLASPADLVKVQIQMEGRRRLMGEPPRVHSAGHAFRQIVQRGGIKGLWKGSIPN 213
            :.|:..||....:..|.|.|||.:|.:..|.     |:.....|.||.||||....||::|....
  Fly    45 VAGLLGGAAGVLVGHPFDTVKVHLQTDDPRN-----PKYKGTFHCFRTIVQRDKFIGLYRGISSP 104

  Fly   214 VQRAALVNLGDLTTYDTIKHLIMNRLQMPDCHTVHVLASVCAGFVAAIMGTPADVVKTRIMNQPT 278
            :....|||......|..::.|..:    |:..|.|..|...||.....:..|.::.|||:  |.:
  Fly   105 MGGIGLVNAIVFGVYGNVQRLSND----PNSLTSHFFAGSIAGVAQGFVCAPMELAKTRL--QLS 163

  Fly   279 DENGRGLLYRGSVDCLRQTVSKEGFVALYKGFLPCWIRMAPWSLTFWLSFEQIRKMIGASG 339
            .:...|:.:.|.:.||:..|..||....:||.....:|..|...::::|||.:.:.:...|
  Fly   164 TQVDSGIKFTGPIHCLKYIVKTEGIRGAFKGLTATILRDIPGFASYFVSFEYLMRQVETPG 224

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ucp4A	NP_001188664.1	PTZ00169	39..335	CDD:240302	51/185 (28%)
		Mito_carr	39..138	CDD:278578
		Mito_carr	142..239	CDD:278578	26/89 (29%)
		Mito_carr	248..336	CDD:278578	23/87 (26%)
CG4995	NP_609380.1	Mito_carr	36..125	CDD:278578	25/84 (30%)
		PTZ00169	41..295	CDD:240302	52/191 (27%)
		Mito_carr	128..218	CDD:278578	25/95 (26%)
		Mito_carr	221..304	CDD:278578	1/4 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45441382
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930