DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ucp4A and Rim2

DIOPT Version :9

Sequence 1:	NP_001188664.1	Gene:	Ucp4A / 32764	FlyBaseID:	FBgn0030872	Length:	340	Species:	Drosophila melanogaster
Sequence 2:	NP_608615.1	Gene:	Rim2 / 33350	FlyBaseID:	FBgn0031359	Length:	365	Species:	Drosophila melanogaster

Alignment Length:	306	Identity:	66/306 - (21%)
Similarity:	108/306 - (35%)	Gaps:	92/306 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 AASIAELATYPLDLTKTRLQIQ-------------GEGAAHSAGKSNMQYRGMVATAFGIAREEG 101
            |.::..:.|.||::.|||||..             |.|.| :.|:|.            :.|.|.
  Fly    18 AGTVGAVVTCPLEVVKTRLQSSTAFMTPSRLAENAGGGPA-NGGQSE------------LLRPEQ 69

  Fly   102 ALKLWQGVTPALYRHVVYSGVRICSYDLMRKEFTQNGTQALPVWKSALCGVTAGAVAQWLASPAD 166
            ..||...:.....:..|..|||                   .:...:.||:::       .:|..
  Fly    70 RRKLSTTILRNRSQPQVIGGVR-------------------RIMAISHCGISS-------TTPKS 108

  Fly   167 LVKVQIQMEGRRRLMGEPPRVHSAGHAFRQIVQRGGIKGLWKGSIPNVQRAALVNLGDLTTYDTI 231
            :..||                     ..|.|||..|.:.|:||..||:...|........||...
  Fly   109 MSIVQ---------------------CLRHIVQNEGPRALFKGLGPNLVGVAPSRAIYFCTYSQT 152

  Fly   232 KHLIMNRLQM--PDCHTVHVLASVCAGFVAAIMGTPADVVKTRIMNQPTDENGRGLLYRGSV--- 291
            |: .:|.|..  .|...||::::..||||::....|...||||:.          |.|...|
  Fly   153 KN-TLNSLGFVERDSPLVHIMSAASAGFVSSTATNPIWFVKTRMQ----------LDYNSKVQMT 206

  Fly   292 --DCLRQTVSKEGFVALYKGFLPCWIRMAPWSLTFWLSFEQIRKMI 335
              .|:.:..::.|..|.|||....:..:.. ::..::.:|.|:..:
  Fly   207 VRQCIERVYAQGGVAAFYKGITASYFGICE-TMVHFVIYEFIKSKL 251

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ucp4A	NP_001188664.1	PTZ00169	39..335	CDD:240302	66/304 (22%)
		Mito_carr	39..138	CDD:278578	22/100 (22%)
		Mito_carr	142..239	CDD:278578	20/96 (21%)
		Mito_carr	248..336	CDD:278578	21/93 (23%)
Rim2	NP_608615.1	Mito_carr	8..156	CDD:278578	41/198 (21%)
		Mito_carr	163..253	CDD:278578	23/100 (23%)
		Mito_carr	268..355	CDD:278578
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45441711
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930