DRSC/TRiP Functional Genomics Resources

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Protein Alignment Ucp4A and SLC25A34

DIOPT Version :9

Sequence 1:NP_001188664.1 Gene:Ucp4A / 32764 FlyBaseID:FBgn0030872 Length:340 Species:Drosophila melanogaster
Sequence 2:NP_997231.1 Gene:SLC25A34 / 284723 HGNCID:27653 Length:304 Species:Homo sapiens


Alignment Length:306 Identity:93/306 - (30%)
Similarity:149/306 - (48%) Gaps:25/306 - (8%)


- Green bases have known domain annotations that are detailed below.


  Fly    41 ACTYIVSVVAASIAELATYPLDLTKTRLQIQGEGAAHSAGKSNMQYRGMVATAFGIAREEGALKL 105
            |...::...|..:|.:.|.||::.|||||:|||  ..:.|.....|.|.:|:...:||.:|...|
Human     7 AVDLVLGASACCLACVFTNPLEVVKTRLQLQGE--LQARGTYPRPYHGFIASVAAVARADGLWGL 69

  Fly   106 WQGVTPALYRHVVYSGVRICSYDLMRKEFTQNGTQALPVWKSALCGVTAGAVAQWLASPADLVKV 170
            .:|:...|....:.:|||...|.|.    .|.|....| ..:.:.|..|||:..::.|||.|:|.
Human    70 QKGLAAGLLYQGLMNGVRFYCYSLA----CQAGLTQQP-GGTVVAGAVAGALGAFVGSPAYLIKT 129

  Fly   171 QIQMEGRRRLMGEPPRVHSAGH---------AFRQIVQRGGIKGLWKGSIPNVQRAALVNLGDLT 226
            |:|        .:.....:.||         |...|.::.|:.|||:|....|.|..:.:...|.
Human   130 QLQ--------AQTVAAVAVGHQHNHQTVLGALETIWRQQGLLGLWQGVGGAVPRVMVGSAAQLA 186

  Fly   227 TYDTIKHLIMNRLQMP-DCHTVHVLASVCAGFVAAIMGTPADVVKTRIMNQPTDENGRGLLYRGS 290
            |:.:.|..:..:..:| |...|.:...:.:.....::.||.|||.||:.|||.|..|||.||.|.
Human   187 TFASAKAWVQKQQWLPEDSWLVALAGGMISSIAVVVVMTPFDVVSTRLYNQPVDTAGRGQLYGGL 251

  Fly   291 VDCLRQTVSKEGFVALYKGFLPCWIRMAPWSLTFWLSFEQIRKMIG 336
            .||:.:...:||.:|||||..|.::|:.|.::...|.::::||:.|
Human   252 TDCMVKIWRQEGPLALYKGLGPAYLRLGPHTILSMLFWDELRKLAG 297

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Ucp4ANP_001188664.1 PTZ00169 39..335 CDD:240302 92/303 (30%)
Mito_carr 39..138 CDD:278578 30/96 (31%)
Mito_carr 142..239 CDD:278578 26/105 (25%)
Mito_carr 248..336 CDD:278578 32/87 (37%)
SLC25A34NP_997231.1 Mito_carr 2..91 CDD:278578 27/85 (32%)
Solcar 1 4..97 29/95 (31%)
Solcar 2 101..194 26/101 (26%)
Mito_carr <119..197 CDD:278578 21/85 (25%)
Mito_carr 203..295 CDD:278578 33/91 (36%)
Solcar 3 204..295 33/90 (37%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1013743at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.920

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