DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ucp4A and Ucp3

DIOPT Version :9

Sequence 1:	NP_001188664.1	Gene:	Ucp4A / 32764	FlyBaseID:	FBgn0030872	Length:	340	Species:	Drosophila melanogaster
Sequence 2:	NP_037299.1	Gene:	Ucp3 / 25708	RGDID:	3933	Length:	308	Species:	Rattus norvegicus

Alignment Length:	304	Identity:	110/304 - (36%)
Similarity:	171/304 - (56%)	Gaps:	21/304 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 VKFDYADSFACTYIVSVVAASIAELATYPLDLTKTRLQIQGEGAAHSAGKSNMQYRGMVATAFGI 96
            |||..|.:.||          .|:|.|:|||..|.|||||||    :.|..::||||::.|...:
  Rat    15 VKFLGAGTAAC----------FADLLTFPLDTAKVRLQIQGE----NPGVQSVQYRGVLGTILTM 65

  Fly    97 AREEGALKLWQGVTPALYRHVVYSGVRICSYDLMRKEFTQNGTQALPVWKSALCGVTAGAVAQWL 161
            .|.||....:.|:...|:|.:.::.:||..||.:::.:|..||....|....|.|.|.||:|...
  Rat    66 VRTEGPRSPYSGLVAGLHRQMSFASIRIGLYDSVKQFYTPKGTDHSSVAIRILAGCTTGAMAVTC 130

  Fly   162 ASPADLVKVQIQMEGRRRLMGEPPRVHSAGHAFRQIVQRGGIKGLWKGSIPNVQRAALVNLGDLT 226
            |.|.|:|||:.|...|....|| .:......|:|.|.:..|::|||||:.||:.|.|:||..::.
  Rat   131 AQPTDVVKVRFQAMIRLGTGGE-RKYRGTMDAYRTIAREEGVRGLWKGTWPNITRNAIVNCAEMV 194

  Fly   227 TYDTIKHLIMNRLQMPDCHTVHVLASVCAGFVAAIMGTPADVVKTRIMNQPTDENGRGLLYRGSV 291
            |||.||..:::.....|....|.:::..|||.|.::.:|.||||||.||.|.   ||   ||..:
  Rat   195 TYDIIKEKLLDSHLFTDNFPCHFVSAFGAGFCATVVASPVDVVKTRYMNAPP---GR---YRSPL 253

  Fly   292 DCLRQTVSKEGFVALYKGFLPCWIRMAPWSLTFWLSFEQIRKMI 335
            .|:.:.|::||..|.||||:|.::|:..|::..::::||:::.:
  Rat   254 HCMLRMVAQEGPTAFYKGFMPSFLRLGSWNVMMFVTYEQLKRAL 297

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ucp4A	NP_001188664.1	PTZ00169	39..335	CDD:240302	106/295 (36%)
		Mito_carr	39..138	CDD:278578	33/98 (34%)
		Mito_carr	142..239	CDD:278578	37/96 (39%)
		Mito_carr	248..336	CDD:278578	33/88 (38%)
Ucp3	NP_037299.1	Mito_carr	10..107	CDD:278578	37/105 (35%)
		Solcar 1	11..102		36/100 (36%)
		PTZ00169	13..298	CDD:240302	110/304 (36%)
		Mito_carr	109..206	CDD:278578	37/97 (38%)
		Solcar 2	111..202		37/91 (41%)
		Mito_carr	209..299	CDD:278578	34/95 (36%)
		Solcar 3	211..296		34/90 (38%)
		Purine nucleotide binding. /evidence=ECO:0000250	275..297		4/21 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0759
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810