DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ucp4A and Ucp1

DIOPT Version :9

Sequence 1:	NP_001188664.1	Gene:	Ucp4A / 32764	FlyBaseID:	FBgn0030872	Length:	340	Species:	Drosophila melanogaster
Sequence 2:	NP_036814.1	Gene:	Ucp1 / 24860	RGDID:	3931	Length:	307	Species:	Rattus norvegicus

Alignment Length:	322	Identity:	102/322 - (31%)
Similarity:	168/322 - (52%)	Gaps:	28/322 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 VASSTSSNPAPSSGRHQLRPVKFDYADSFACTYIVSVVAASIAELATYPLDLTKTRLQIQGEGAA 76
            :.|||:|...|:.|      ||...|...||          :|::.|:|||..|.||||||||.|
  Rat     1 MVSSTTSEVQPTMG------VKIFSAGVSAC----------LADIITFPLDTAKVRLQIQGEGQA 49

  Fly    77 HSAGKSNMQYRGMVATAFGIAREEGALKLWQGVTPALYRHVVYSGVRICSYDLMRKEFTQNGTQA 141
                .|.::|:|::.|...:|:.||..||:.|:...:.|.:.::.:||..||.:::.|:......
  Rat    50 ----SSTIRYKGVLGTITTLAKTEGLPKLYSGLPAGIQRQISFASLRIGLYDTVQEYFSSGRETP 110

  Fly   142 LPVWKSALCGVTAGAVAQWLASPADLVKVQIQMEGRRRLMGEPPRVHSAGHAFRQIVQRGGIKGL 206
            ..:......|:..|.||.::..|.::|||  :|:.:..|.|..||.....:|:|.|.....:..|
  Rat   111 ASLGSKISAGLMTGGVAVFIGQPTEVVKV--RMQAQSHLHGIKPRYTGTYNAYRVIATTESLSTL 173

  Fly   207 WKGSIPNVQRAALVNLGDLTTYDTIKHLIMNRLQMPDCHTVHVLASVCAGFVAAIMGTPADVVKT 271
            |||:.||:.|..::|..:|.|||.:|..::|...:.|....|:|:::.|||...::.:|.|||||
  Rat   174 WKGTTPNLMRNVIINCTELVTYDLMKGALVNHHILADDVPCHLLSALVAGFCTTLLASPVDVVKT 238

  Fly   272 RIMNQPTDENGRGLLYRGSVDCLRQTVSKEGFVALYKGFLPCWIRMAPWSLTFWLSFEQIRK 333
            |.:|....:      |.....|.....:|||..|.:|||.|.::|:..|::..::.|||::|
  Rat   239 RFINSLPGQ------YPSVPSCAMTMYTKEGPAAFFKGFAPSFLRLGSWNVIMFVCFEQLKK 294

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ucp4A	NP_001188664.1	PTZ00169	39..335	CDD:240302	93/295 (32%)
		Mito_carr	39..138	CDD:278578	33/98 (34%)
		Mito_carr	142..239	CDD:278578	30/96 (31%)
		Mito_carr	248..336	CDD:278578	29/86 (34%)
Ucp1	NP_036814.1	Mito_carr	10..103	CDD:278578	37/112 (33%)
		Solcar 1	11..102		37/110 (34%)
		PTZ00169	21..297	CDD:240302	93/296 (31%)
		Mito_carr	110..205	CDD:278578	29/96 (30%)
		Solcar 2	111..201		29/91 (32%)
		Solcar 3	210..295		30/91 (33%)
		Mito_carr	215..300	CDD:278578	29/86 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0759
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810