DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ucp4A and SLC25A10

DIOPT Version :9

Sequence 1:	NP_001188664.1	Gene:	Ucp4A / 32764	FlyBaseID:	FBgn0030872	Length:	340	Species:	Drosophila melanogaster
Sequence 2:	NP_001257882.1	Gene:	SLC25A10 / 1468	HGNCID:	10980	Length:	406	Species:	Homo sapiens

Alignment Length:	182	Identity:	53/182 - (29%)
Similarity:	86/182 - (47%)	Gaps:	22/182 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 VAASIAELATYPLDLTKTRLQIQGEGAAHSAGKSNMQYRGMVATAFGIAREEGALKLWQGVTPAL 113
            :|:..|...|:||||.|..||.|.|          ::.| |...|..:.|.:|.|.|:.|::.:|
Human    15 LASCGAACCTHPLDLLKVHLQTQQE----------VKLR-MTGMALRVVRTDGILALYSGLSASL 68

  Fly   114 YRHVVYSGVRICSYDLMRKEFTQNGTQALPVWKSALCGVTAGAVAQWLASPADLVKVQIQ----- 173
            .|.:.||..|...|:.:|....:.....||..:..|.|..:|....::.:|||||.|::|
Human    69 CRQMTYSLTRFAIYETVRDRVAKGSQGPLPFHEKVLLGSVSGLAGGFVGTPADLVNVRMQNDVKL 133

  Fly   174 MEGRRRLMGEPPRVHSAGHAFRQIVQRGGIKGLWKGSIPNVQRAALVNLGDL 225
            .:|:||     ...|:....:| :.:..|::.|:.|:.....|.|||.:|.|
Human   134 PQGQRR-----NYAHALDGLYR-VAREEGLRRLFSGATMASSRGALVTVGQL 179

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ucp4A	NP_001188664.1	PTZ00169	39..335	CDD:240302	53/182 (29%)
		Mito_carr	39..138	CDD:278578	27/88 (31%)
		Mito_carr	142..239	CDD:278578	26/89 (29%)
		Mito_carr	248..336	CDD:278578
SLC25A10	NP_001257882.1	Mito_carr	13..93	CDD:278578	27/88 (31%)
SLC25A10	NP_001257882.1	Mito_carr	95..179	CDD:278578	25/89 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0759
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810