DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8142 and Rfc3

DIOPT Version :9

Sequence 1:	NP_573245.1	Gene:	CG8142 / 32763	FlyBaseID:	FBgn0030871	Length:	353	Species:	Drosophila melanogaster
Sequence 2:	NP_081285.1	Gene:	Rfc3 / 69263	MGIID:	1916513	Length:	356	Species:	Mus musculus

Alignment Length:	268	Identity:	85/268 - (31%)
Similarity:	126/268 - (47%)	Gaps:	45/268 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 WVEKYRPRNVDDVVEQSEVVAVLRKCVEGGDLPNMLLYGPPGTGKTSTILAASRQIFG-DMFKDR 95
            ||:||||.::..:....|..|.||..|:.||.|::|:|||.|.||.:.|:...|:::| .:.|.|
Mouse     4 WVDKYRPSSLARLDYHKEQAAQLRNLVQCGDFPHLLVYGPSGAGKKTRIMCILRELYGIGVEKLR 68

  Fly    96 I-----------------------LELNASDERGIN--VVRTKIKNFS---QLSASSVRPDGKPC 132
            |                       ||:|.||....:  |::..:|..:   ||..||.|
Mouse    69 IEHQTITTPSKKKIEISTIASNYHLEVNPSDAGNSDRVVIQEMLKTVAQSQQLETSSQR------ 127

  Fly   133 PPFKIIILDEADSMTHAAQSALRRTMEKESRSTRFCLICNYVSRIIVPITSRCSKFRFKALGEDK 197
             .||:::|.|.|.:|..||.||||||||...:.|..|.||..|::|.||.|||...|..|...:.
Mouse   128 -DFKVVLLTEVDKLTKDAQHALRRTMEKYMSTCRLILCCNSTSKVIPPIRSRCLAVRVPAPSIED 191

  Fly   198 VIDRLKYICEMEGVKIEDDAYKSIVKISGGDLRRAITTLQSCYRLKGPEHIINTADLFEMSGVIP 262
            :...|..:|..||:.:.....:.:.:.|..:||:|:...::|...:.|         |.....||
Mouse   192 ICSVLSTVCRKEGLALPSTLARRLAEKSCRNLRKALLMCEACRVQQYP---------FTEDQEIP 247

  Fly   263 EYYLEDYL 270
            |...|.||
Mouse   248 ETDWEVYL 255

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8142	NP_573245.1	rfc	31..344	CDD:234763	85/268 (32%)
		AAA	45..187	CDD:99707	60/170 (35%)
		AAA_assoc_2	211..>256	CDD:292811	6/44 (14%)
		Rep_fac_C	<293..344	CDD:285713
Rfc3	NP_081285.1	PRK12402	3..339	CDD:237090	85/268 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0470
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1071197at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820