DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8142 and rfc4

DIOPT Version :9

Sequence 1:	NP_573245.1	Gene:	CG8142 / 32763	FlyBaseID:	FBgn0030871	Length:	353	Species:	Drosophila melanogaster
Sequence 2:	NP_001016363.1	Gene:	rfc4 / 549117	XenbaseID:	XB-GENE-955724	Length:	360	Species:	Xenopus tropicalis

Alignment Length:	355	Identity:	198/355 - (55%)
Similarity:	254/355 - (71%)	Gaps:	15/355 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MQAFLKTGKS---------TAGSGDKSQGTPAARRKPPAPWVEKYRPRNVDDVVEQSEVVAVLRK 56
            ||||||.|.|         .:.||..|.|  .::::.|.||||||||:.||:|..|.||||||:|
Frog     1 MQAFLKGGTSISTKPVKDKASASGTGSTG--ESKKQKPVPWVEKYRPKCVDEVAFQEEVVAVLKK 63

  Fly    57 CVEGGDLPNMLLYGPPGTGKTSTILAASRQIFG-DMFKDRILELNASDERGINVVRTKIKNFSQL 120
            .:||.||||:|.|||||||||||||||||:::| ::|:.|:|||||||||||.|||.|:|||:||
Frog    64 SLEGADLPNLLFYGPPGTGKTSTILAASRELYGPELFRQRVLELNASDERGIQVVREKVKNFAQL 128

  Fly   121 SASSVRPDGKPCPPFKIIILDEADSMTHAAQSALRRTMEKESRSTRFCLICNYVSRIIVPITSRC 185
            :....|.||||||||||:|||||||||.|||:||||||||||::||||||||||||||.|:||||
Frog   129 TVGGTRSDGKPCPPFKIVILDEADSMTSAAQAALRRTMEKESKTTRFCLICNYVSRIIEPLTSRC 193

  Fly   186 SKFRFKALGEDKVIDRLKYICEMEGVKIEDDAYKSIVKISGGDLRRAITTLQSCYRLKGPEHIIN 250
            ||||||.|.:.....||..|||.|.|||.::|...:|::|.||||:|||.|||..||.|.:.|
Frog   194 SKFRFKPLADKIQTQRLLSICEKENVKITNEAISCLVEVSEGDLRKAITFLQSATRLTGGKEI-- 256

  Fly   251 TADLF-EMSGVIPEYYLEDYLEVCRSGNYERLEQFVREIGFSAYSVGQMMEQFVEFIVHHPGLND 314
            |.::. |::||:|:..|:..|..|:||::|:||..|:.:..:.::..|::.|..:.|:....|.|
Frog   257 TEEIVTEIAGVVPKETLDCVLVACQSGSFEKLETVVKNLINNGHAATQLVNQLHDVILERGDLTD 321

  Fly   315 PQKATICDKLGECCFRLQDGGSEYLQIMDL 344
            .|||.|.:||.|....|.||..||||::.|
Frog   322 KQKAFITEKLAEVDKCLADGADEYLQMLGL 351

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8142	NP_573245.1	rfc	31..344	CDD:234763	184/314 (59%)
		AAA	45..187	CDD:99707	107/142 (75%)
		AAA_assoc_2	211..>256	CDD:292811	21/45 (47%)
		Rep_fac_C	<293..344	CDD:285713	19/50 (38%)
rfc4	NP_001016363.1	rfc	38..353	CDD:234763	185/316 (59%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	204	1.000	Domainoid score	I2887
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6288
Inparanoid	1	1.050	354	1.000	Inparanoid score	I2202
OMA	1	1.010	-	-		QHG53599
OrthoDB	1	1.010	-	-		D1071197at2759
OrthoFinder	1	1.000	-	-		FOG0000505
OrthoInspector	1	1.000	-	-		oto103227
Panther	1	1.100	-	-	LDO	PTHR11669
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3510
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	11.080