DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8142 and Rad17

DIOPT Version :9

Sequence 1:	NP_573245.1	Gene:	CG8142 / 32763	FlyBaseID:	FBgn0030871	Length:	353	Species:	Drosophila melanogaster
Sequence 2:	NP_001019949.1	Gene:	Rad17 / 310034	RGDID:	1309515	Length:	686	Species:	Rattus norvegicus

Alignment Length:	267	Identity:	63/267 - (23%)
Similarity:	106/267 - (39%)	Gaps:	75/267 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 PWVEKYRPRNVDDVVEQSEVVAVLRKCVE-----------------GGDLPNMLLYGPPGTGKTS 78
            |||:||:|       |....:||.:|.:|                 ||.:  :|:.||||.|||:
  Rat    89 PWVDKYKP-------ETQHELAVHKKKIEEVETWLKTQVLEVKPKHGGSI--LLITGPPGCGKTT 144

  Fly    79 TILAASRQ-----------IFGDMFKDRILEL-NASDERGINVVRTKIKNFS------------Q 119
            ||...|::           |..|..||...|| |:.....:...:::|..|:            |
  Rat   145 TIKILSKELGIQVQEWVNPILQDFQKDDYKELFNSESNFSVIPYQSQIAVFNDFLLRATKYNKLQ 209

  Fly   120 LSASSVRPDGKPCPPFKIIILDEADSMTHAAQSALRRTMEKE---SRSTRFCLICNYVS-----R 176
            :...::..|.      |||::::..:..:...:||...:.|.   .|.....::.:.||     |
  Rat   210 MLGDALTTDK------KIILVEDLPNQFYRDANALHEILRKYVHIGRCPLVFIVSDSVSGDSNHR 268

  Fly   177 IIVP--ITSRC--SKFRFKALGEDKVIDRLKYICEME----GVKI---EDDAYKSIVKISGGDLR 230
            ::.|  |...|  |...|..:....::..|..|..:|    |.||   ...:.:.:.:...||:|
  Rat   269 LLFPKNIQEECSVSNISFNPVAPTIMMKFLNRIVTIEASKNGEKITVPNKASLELLCQGCSGDIR 333

  Fly   231 RAITTLQ 237
            .||.:||
  Rat   334 SAINSLQ 340

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8142	NP_573245.1	rfc	31..344	CDD:234763	63/267 (24%)
		AAA	45..187	CDD:99707	42/194 (22%)
		AAA_assoc_2	211..>256	CDD:292811	9/30 (30%)
		Rep_fac_C	<293..344	CDD:285713
Rad17	NP_001019949.1	rad24	13..651	CDD:129690	63/267 (24%)
Rad17	NP_001019949.1	AAA_18	133..>253	CDD:289979	29/125 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0470
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900