DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8142 and rfc-3

DIOPT Version :9

Sequence 1:	NP_573245.1	Gene:	CG8142 / 32763	FlyBaseID:	FBgn0030871	Length:	353	Species:	Drosophila melanogaster
Sequence 2:	NP_502517.1	Gene:	rfc-3 / 178259	WormBaseID:	WBGene00004339	Length:	354	Species:	Caenorhabditis elegans

Alignment Length:	308	Identity:	91/308 - (29%)
Similarity:	143/308 - (46%)	Gaps:	72/308 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 APWVEKYRPRN------VDDVVEQSEVVAVLRKCVEGGDLPNMLLYGPPGTGKTSTILAASRQIF 88
            |.||:||||::      ||..:||:..:    |.:....:|::|..||.|.||.:.|....|:::
Worm     2 ALWVDKYRPKDLLGKDGVDYHIEQANHL----KFLSADCMPHLLFCGPSGAGKKTRIKCLLRELY 62

  Fly    89 G-DMFKDRI-----------------------LELNASDERGIN---VVRTKIKNF---SQLSAS 123
            | .:.|.::                       :|:..||. ||.   ||:..:|..   ||:.::
Worm    63 GVGVEKTQLIMKSFTSPSNKKLEIQTVSSNYHIEMTPSDV-GIYDRVVVQDLVKEMAQTSQIEST 126

  Fly   124 SVRPDGKPCPPFKIIILDEADSMTHAAQSALRRTMEKESRSTRFCLICNYVSRIIVPITSRCSKF 188
            |.|       .||:::|.||||:|..||..|||||||.:.:.:..|.|..:||||.|:.|||...
Worm   127 SQR-------SFKVVVLCEADSLTRDAQHGLRRTMEKYANNCKIVLSCESLSRIIEPLQSRCIII 184

  Fly   189 RFKALGEDKVIDRLKYICEMEGVKIEDDAYKSIVKISGGDLRRAITTLQSCYRLKGPEHIINTAD 253
            ...|..::.|...|:.:.|.|...:.::..:.||:.|.|:||||| .:....|::      |.:.
Worm   185 NVPAPTDEDVTKVLRKVIERESFLLPENVLQKIVEKSEGNLRRAI-LMTEALRME------NESG 242

  Fly   254 LFEMSGVIP----EYYLE------------DYLEVCRSGNYERLEQFV 285
            :.| |.|||    |.|::            |.|...|...||.|.:.:
Worm   243 VAE-SVVIPVPEWEIYIQETARLILQKQSSDMLLKVRERLYELLSRCI 289

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8142	NP_573245.1	rfc	31..344	CDD:234763	90/307 (29%)
		AAA	45..187	CDD:99707	53/171 (31%)
		AAA_assoc_2	211..>256	CDD:292811	11/44 (25%)
		Rep_fac_C	<293..344	CDD:285713
rfc-3	NP_502517.1	PRK12402	3..342	CDD:237090	90/307 (29%)
		AAA	38..187	CDD:99707	50/156 (32%)
		Rep_fac_C	253..340	CDD:285713	8/37 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0470
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1071197at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820