DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8142 and mdt-30

DIOPT Version :9

Sequence 1:	NP_573245.1	Gene:	CG8142 / 32763	FlyBaseID:	FBgn0030871	Length:	353	Species:	Drosophila melanogaster
Sequence 2:	NP_498749.1	Gene:	mdt-30 / 176130	WormBaseID:	WBGene00004125	Length:	466	Species:	Caenorhabditis elegans

Alignment Length:	259	Identity:	47/259 - (18%)
Similarity:	97/259 - (37%)	Gaps:	94/259 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 KTG----KSTAGSGDKSQGTPAARRKP-----PAPW----VEKYRPRN--------VDDV-VEQS 48
            :||    :::|.|..::|.|.|.:.:|     .:|.    :|||....        |:|: |:.|
Worm   237 QTGHPPQQTSASSQQRAQETMAQQTEPQSHIRESPQKETNLEKYSTGELCLYGRELVNDLNVKTS 301

  Fly    49 EVVAVLRKCVE-----GGDLPNMLLYGPPGTGKTSTILAASRQIFGDMFKDRILELNASDERGIN 108
            .:..:|:|.:|     .|:.||.|                     .|..|:.:..:  ||.|.|
Worm   302 YLSTILKKVMERKPLNQGENPNDL---------------------ADQCKNALQRM--SDIRQI- 342

  Fly   109 VVRTKIKNFSQLSASSVRPDGKPCPPFKIIILDEADSMTHAAQSALRRTMEKESR------STRF 167
            :.:.:...:.:::...          :..::||:         |.|::.|::|.:      ..||
Worm   343 IEKRREPTWKRMTGED----------YIELMLDD---------SELKKPMDEERQKRRAELEQRF 388

  Fly   168 CLICNYVSRIIVPITSRCSKFRFKALGEDKVIDRLKYIC-EMEGVKIEDDAYKSIVKISGGDLR 230
            .::.:....:                 |..:..:.|:|. |:....::.:|.|.|||....:|:
Worm   389 AIVISKTPPV-----------------EGHIWYQGKWISEELHKKYMQFEANKEIVKNLAAELK 435

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8142	NP_573245.1	rfc	31..344	CDD:234763	39/225 (17%)
		AAA	45..187	CDD:99707	23/152 (15%)
		AAA_assoc_2	211..>256	CDD:292811	6/20 (30%)
		Rep_fac_C	<293..344	CDD:285713
mdt-30	NP_498749.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0470
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900