DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment e(y)1 and taf9

DIOPT Version :9

Sequence 1:	NP_523391.3	Gene:	e(y)1 / 32762	FlyBaseID:	FBgn0000617	Length:	278	Species:	Drosophila melanogaster
Sequence 2:	NP_001037860.2	Gene:	taf9 / 321485	ZFINID:	ZDB-GENE-030131-204	Length:	248	Species:	Danio rerio

Alignment Length:	248	Identity:	104/248 - (41%)
Similarity:	137/248 - (55%)	Gaps:	31/248 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 AQIKHVPKDAQVIMSILKELNVQEYEPRVVNQLLEFTFRYVTCILDDAKVYANHARKKTIDLDDV 77
            |..|.|||||||:|.|||::.:.|||||||||:||||:||||.|::|||:|:.||:|.::|.||:
Zfish     2 ASPKTVPKDAQVMMQILKDMGITEYEPRVVNQMLEFTYRYVTTIIEDAKIYSAHAKKSSVDADDI 66

  Fly    78 RLATEVTLDKSFTGPLERHVLAKVADVRNSMPLPPIKPHCGLRLPPDRYCLTGVNYKLRATNQPK 142
            |||.:..:|:|||.|..|..|..:|..:|..|||.|||:.|.||||||||||..||:|::..  |
Zfish    67 RLAIQCRVDQSFTSPPPRDFLLDIARQKNQTPLPLIKPYTGPRLPPDRYCLTAPNYRLKSLQ--K 129

  Fly   143 KMTKS------------AVEGRP-LKTVVKPVSSANGPK--RPHSVVAKQQVVTIPK---PVIKF 189
            |::.|            ||..|| ..|:..|.....|.|  .|.|:..::..|.||.   ..:|.
Zfish   130 KVSSSAGRITVPRLSVGAVSSRPSTPTLGTPSVQTVGTKVGTPVSLTGQRFTVQIPSSQTASVKS 194

  Fly   190 TTTTT---------TKTVGSSG--GSGGGGGQEVKSESTGAGGDLKMEVDSDA 231
            .|.||         ...:||..  .:.....|...||||......:.|.|.||
Zfish   195 ATPTTPTVQNVLINPSLIGSKNILITTNMVSQNSSSESTSLKRKHEDEDDYDA 247

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
e(y)1	NP_523391.3	TFIID-31kDa	16..135	CDD:280456	71/118 (60%)
taf9	NP_001037860.2	TFIID-31kDa	4..124	CDD:280456	71/119 (60%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170574399
Domainoid	1	1.000	157	1.000	Domainoid score	I4125
eggNOG	1	0.900	-	-		E1_COG5094
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	162	1.000	Inparanoid score	I4196
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1429345at2759
OrthoFinder	1	1.000	-	-		FOG0003046
OrthoInspector	1	1.000	-	-		oto40628
orthoMCL	1	0.900	-	-		OOG6_101921
Panther	1	1.100	-	-	LDO	PTHR48068
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2308
SonicParanoid	1	1.000	-	-		X2395
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	15	14.790