DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment e(y)1 and Taf9

DIOPT Version :9

Sequence 1:	NP_523391.3	Gene:	e(y)1 / 32762	FlyBaseID:	FBgn0000617	Length:	278	Species:	Drosophila melanogaster
Sequence 2:	NP_001015889.1	Gene:	Taf9 / 108143	MGIID:	1888697	Length:	264	Species:	Mus musculus

Alignment Length:	208	Identity:	91/208 - (43%)
Similarity:	125/208 - (60%)	Gaps:	24/208 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 AQIKHVPKDAQVIMSILKELNVQEYEPRVVNQLLEFTFRYVTCILDDAKVYANHARKKTIDLDDV 77
            |..|.:|||||::..|||::.:.||||||:||:|||.|||||.||||||:|::||:|.|:|.|||
Mouse     7 ASPKSMPKDAQMMAQILKDMGITEYEPRVINQMLEFAFRYVTTILDDAKIYSSHAKKATVDADDV 71

  Fly    78 RLATEVTLDKSFTGPLERHVLAKVADVRNSMPLPPIKPHCGLRLPPDRYCLTGVNYKLRATNQP- 141
            |||.:...|:|||.|..|..|..:|..||..|||.|||:.|.||||||||||..||:|::..:.
Mouse    72 RLAIQCRADQSFTSPPPRDFLLDIARQRNQTPLPLIKPYSGPRLPPDRYCLTAPNYRLKSLQKKA 136

  Fly   142 ---------KKMTKSAVEGRP-LKTVVKP------VSSANGPKRPHSVVAKQQVVTIP---KPVI 187
                     .:::..:|..|| ..|:..|      ||:..|  .|.|:..::..|.:|   .|.:
Mouse   137 PAPAGRITVPRLSVGSVSSRPSTPTLGTPTPQTMSVSTKVG--TPMSLTGQRFTVQMPASQSPAV 199

  Fly   188 K--FTTTTTTKTV 198
            |  ...|:|.:.|
Mouse   200 KASIPATSTVQNV 212

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
e(y)1	NP_523391.3	TFIID-31kDa	16..135	CDD:280456	72/118 (61%)
Taf9	NP_001015889.1	TFIID-31kDa	9..130	CDD:396739	72/120 (60%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	150..176		7/25 (28%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	233..264
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167831406
Domainoid	1	1.000	157	1.000	Domainoid score	I4150
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	172	1.000	Inparanoid score	I4086
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003046
OrthoInspector	1	1.000	-	-		otm43125
orthoMCL	1	0.900	-	-		OOG6_101921
Panther	1	1.100	-	-	O	PTHR48068
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2308
SonicParanoid	1	1.000	-	-		X2395
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.880