Protein Alignment CG6398 and Tmem178b

DIOPT Version :10

• Sequence 1: NP_573244.1
• Gene: CG6398 / 32761
• FlyBaseID: FBgn0030870
• Length: 290
• Species: Drosophila melanogaster
• Sequence 2: NP_001347907.1
• Gene: Tmem178b / 434008
• MGIID: 3647581
• Length: 294
• Species: Mus musculus
• Alignment Length: 275
• Identity: 57/275 - (20%)
• Similarity: 92/275 - (33%)
• Gaps: 77/275 - (28%)

  Fly     8 LSIATICAIIATALLAIAFSTDNWLHYDV--WRNQIQSFAAKHSDAESLLHNMN----------- 59
            ||:| :||:   .:||:|..:|:|...|.  .|::.::|..:..|...:.:|.|
Mouse    12 LSLA-LCAL---GMLAVAICSDHWYETDARKHRDRCKAFNTRRVDPGFIYNNNNNLPLRASRSRL 72

  Fly    60 ------------------------VKYYYYTRTRGLFRICYPKERPPVSAVPTYLSPIETHCSNI 100
                                    ....|.:...||:|.|:.:...|..|.......|| .|:.|
Mouse    73 DRWEGKLLRARNRRQLFAMSPADECSRQYNSTNMGLWRKCHRQGFDPEIAALIRKGEIE-RCTYI 136

  Fly   101 DYFPQAED---------EKIANEDATSRLHLARSCIALFIISFVTIFCAFWTGLSG-CWKRSSGA 155
            .|...:..         .|...:|....|||.|.......::...|...:..|:.| ||.|....
Mouse   137 KYHYSSATIPRNLTFNITKTIRQDEWHALHLRRMTAGFMGMAVAIILFGWIIGVLGCCWDRGLMQ 201

  Fly   156 ITATSILL---------LVTCLLAAGAMGLWHTVEFFEKEKVVGEDYFQQWNTVLRDNTKIAYDW 211
            ..|..:.|         |.||:....          ||..:      :.::...|.|:....|.|
Mouse   202 YVAGLLFLMGGTFCIISLCTCVAGIN----------FELSR------YPRYLYGLPDDISHGYGW 250

  Fly   212 SYIVAWAGIGTCLLA 226
            |...||.|:|..|::
Mouse   251 SMFCAWGGLGLTLIS 265

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6398	NP_573244.1	Claudin_2	16..232	CDD:372799	52/267 (19%)
Tmem178b	NP_001347907.1	PMP22_Claudin	100..266	CDD:473919	41/183 (22%)