Protein Alignment CG6398 and TMEM178B

DIOPT Version :9

• Sequence 1: NP_001285391.1
• Gene: CG6398 / 32761
• FlyBaseID: FBgn0030870
• Length: 290
• Species: Drosophila melanogaster
• Sequence 2: NP_001182207.1
• Gene: TMEM178B / 100507421
• HGNCID: 44112
• Length: 294
• Species: Homo sapiens
• Alignment Length: 275
• Identity: 57/275 - (20%)
• Similarity: 92/275 - (33%)
• Gaps: 77/275 - (28%)

  Fly     8 LSIATICAIIATALLAIAFSTDNWLHYDV--WRNQIQSFAAKHSDAESLLHNMN----------- 59
            ||:| :||:   .:||:|..:|:|...|.  .|::.::|..:..|...:.:|.|
Human    12 LSLA-LCAL---GMLAVAICSDHWYETDARKHRDRCKAFNTRRVDPGFIYNNNNNLPLRASRSRL 72

  Fly    60 ------------------------VKYYYYTRTRGLFRICYPKERPPVSAVPTYLSPIETHCSNI 100
                                    ....|.:...||:|.|:.:...|..|.......|| .|:.|
Human    73 DRWEGKLLRARNRRQLFAMSPADECSRQYNSTNMGLWRKCHRQGFDPEIAALIRKGEIE-RCTYI 136

  Fly   101 DYFPQAED---------EKIANEDATSRLHLARSCIALFIISFVTIFCAFWTGLSG-CWKRSSGA 155
            .|...:..         .|...:|....|||.|.......::...|...:..|:.| ||.|....
Human   137 KYHYSSATIPRNLTFNITKTIRQDEWHALHLRRMTAGFMGMAVAIILFGWIIGVLGCCWDRGLMQ 201

  Fly   156 ITATSILL---------LVTCLLAAGAMGLWHTVEFFEKEKVVGEDYFQQWNTVLRDNTKIAYDW 211
            ..|..:.|         |.||:....          ||..:      :.::...|.|:....|.|
Human   202 YVAGLLFLMGGTFCIISLCTCVAGIN----------FELSR------YPRYLYGLPDDISHGYGW 250

  Fly   212 SYIVAWAGIGTCLLA 226
            |...||.|:|..|::
Human   251 SMFCAWGGLGLTLIS 265

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6398	NP_001285391.1	Claudin_2	16..232	CDD:290614	52/267 (19%)
TMEM178B	NP_001182207.1	PMP22_Claudin	100..266	CDD:389833	41/183 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.000