Protein Alignment Socs16D and SOCS2

DIOPT Version :10

• Sequence 1: NP_001259662.1
• Gene: Socs16D / 32760
• FlyBaseID: FBgn0030869
• Length: 1021
• Species: Drosophila melanogaster
• Sequence 2: XP_016875636.1
• Gene: SOCS2 / 8835
• HGNCID: 19382
• Length: 243
• Species: Homo sapiens
• Alignment Length: 191
• Identity: 57/191 - (29%)
• Similarity: 93/191 - (48%)
• Gaps: 22/191 - (11%)

  Fly   833 PRALQFTSSIEKVKDYGWYWGPLSSEAAEKVLSSEPDGSFIVRDSSDDHYIFSLSFKLNNCVRHV 897
            |:|.:...::.::...|||||.::...|::.|...|:|:|::||||...|:.::|.|.:....::
Human    31 PQAARLAKALRELGQTGWYWGSMTVNEAKEKLKEAPEGTFLIRDSSHSDYLLTISVKTSAGPTNL 95

  Fly   898 RIEQDQGTFSFGSYAKFKSQ-----TITEFIEKAVE---HSRSGRYLFFLHRRPEHGPMRVQLTN 954
            |||...|.|...|....||:     ::...|:..|:   ..|:|      ...|.:|.:.:.||.
Human    96 RIEYQDGKFRLDSIICVKSKLKQFDSVVHLIDYYVQMCKDKRTG------PEAPRNGTVHLYLTK 154

  Fly   955 PVSRFKHVQSLQHMCRFVILKAVIRKDLIQTLPLPRRLLDYLNYKHCYSEQVESDSSHSQI 1015
            |:  :....||||:||..|.|..   ..|..||||.||.|||..   |..||::.....::
Human   155 PL--YTSAPSLQHLCRLTINKCT---GAIWGLPLPTRLKDYLEE---YKFQVQAPVGEKEL 207

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Socs16D	NP_001259662.1	SH2_SOCS7	839..937	CDD:198251	29/105 (28%)
		SOCS_SOCS7	960..1009	CDD:239710	21/48 (44%)
SOCS2	XP_016875636.1	SH2_SOCS2	40..142	CDD:198246	29/107 (27%)
		SOCS_SOCS2	158..198	CDD:239705	19/45 (42%)