DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Socs16D and SLA2

DIOPT Version :9

Sequence 1:	NP_001259662.1	Gene:	Socs16D / 32760	FlyBaseID:	FBgn0030869	Length:	1021	Species:	Drosophila melanogaster
Sequence 2:	XP_016883587.1	Gene:	SLA2 / 84174	HGNCID:	17329	Length:	288	Species:	Homo sapiens

Alignment Length:	196	Identity:	47/196 - (23%)
Similarity:	74/196 - (37%)	Gaps:	61/196 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   800 PLPKKALPFTAAAYAIEA---VKSEPEEVKTNAIQ-----------------EP----------- 833
            |..:|:||..:.:.:::.   |..|.|..|..|:.                 ||
Human     5 PSRRKSLPSPSLSSSVQGQGPVTMEAERSKATAVALGSFPAGGPAELSLRLGEPLTIVSEDGDWW 69

  Fly   834 --------RALQFTS-SIEKVKDYGWYWGPLSSEAAEK--VLSSEPDGSFIVRDSSDDHYIFSLS 887
                    |.....| .:.|| .:||.:..||.|.||:  :|...|.|:|::|:|......:|||
Human    70 TVLSEVSGREYNIPSVHVAKV-SHGWLYEGLSREKAEELLLLPGNPGGAFLIRESQTRRGSYSLS 133

  Fly   888 FKLN-----NCVRHVRIE-QDQGTFSFGSYAKFKSQTITEFIEKAVEH----SRSGRYLFFLHRR 942
            .:|:     :.:||.||. .|.|.........|.|      ::..|:|    .:||  |.:.|..
Human   134 VRLSRPASWDRIRHYRIHCLDNGWLYISPRLTFPS------LQALVDHYSDRQKSG--LPYFHAS 190

  Fly   943 P 943
            |
Human   191 P 191

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Socs16D	NP_001259662.1	SH2_SOCS7	839..937	CDD:198251	32/110 (29%)
Socs16D	NP_001259662.1	SOCS_SOCS7	960..1009	CDD:239710
SLA2	XP_016883587.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910