DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Socs16D and Cish

DIOPT Version :9

Sequence 1:	NP_001259662.1	Gene:	Socs16D / 32760	FlyBaseID:	FBgn0030869	Length:	1021	Species:	Drosophila melanogaster
Sequence 2:	NP_113992.1	Gene:	Cish / 83681	RGDID:	69261	Length:	257	Species:	Rattus norvegicus

Alignment Length:	240	Identity:	62/240 - (25%)
Similarity:	96/240 - (40%)	Gaps:	62/240 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   797 ALPPLPKKALPFTAAAYAIEAVKSEPEEVKTNAIQEPRALQ-------FTSSIEKVKDYGWYWGP 854
            |:.|||..|.|           :...||....:..||:.|.       ...:...:::.|||||.
  Rat    33 AMQPLPTGAFP-----------EEVTEETPVQSENEPKVLDPEGDLLCIAKTFSYLRESGWYWGS 86

  Fly   855 LSSEAAEKVLSSEPDGSFIVRDSSDDHYIFSLSFKLNNCVRHVRIEQDQGTFSFGSYAKFKSQ-- 917
            :::..|.:.|...|:|:|:||||:...|:|:||.|......:||||....:|...|....:.:
  Rat    87 ITASEARQHLQKMPEGTFLVRDSTHPSYLFTLSVKTTRGPTNVRIEYADSSFRLDSNCLSRPRIL 151

  Fly   918 -------TITEFIEKAVEHSRSGRYLFFLHRRPEHGP------------------------MRVQ 951
                   .:..::......:||.        .|:..|                        :.::
  Rat   152 AFPDVVSLVQHYVASCTADTRSD--------SPDPAPTPALPVPKPDAPGDPVLPIPVATAVHLK 208

  Fly   952 LTNPVSRFKHVQSLQHMCRFVILKAVIRKDLIQTLPLPRRLLDYL 996
            |..|..|....:||||:||.||.:.|...|   .||||||:.|||
  Rat   209 LVQPFVRRSSARSLQHLCRLVINRLVTDVD---CLPLPRRMADYL 250

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Socs16D	NP_001259662.1	SH2_SOCS7	839..937	CDD:198251	27/106 (25%)
Socs16D	NP_001259662.1	SOCS_SOCS7	960..1009	CDD:239710	19/37 (51%)
Cish	NP_113992.1	SH2_CIS	77..164	CDD:198285	25/86 (29%)
Cish	NP_113992.1	SOCS_CIS1	217..257	CDD:239703	19/37 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4566
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	4	3.770