DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Socs16D and socs2

DIOPT Version :9

Sequence 1:	NP_001259662.1	Gene:	Socs16D / 32760	FlyBaseID:	FBgn0030869	Length:	1021	Species:	Drosophila melanogaster
Sequence 2:	XP_005164804.1	Gene:	socs2 / 562062	ZFINID:	ZDB-GENE-041210-171	Length:	198	Species:	Danio rerio

Alignment Length:	190	Identity:	59/190 - (31%)
Similarity:	98/190 - (51%)	Gaps:	17/190 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   816 EAVKSEPEEVKTNAIQEPRALQFTSSIEKVKD-YGWYWGPLSSEAAEKVLSSEPDGSFIVRDSSD 879
            |::::|........:.:....:..:::..:|: .|||||.|::..|:::|....:|:|:|||||.
Zfish    10 ESIENERRSQSETQVADTEQSRIATAMRDLKNTAGWYWGSLTANEAKEILQDTSEGTFLVRDSSQ 74

  Fly   880 DHYIFSLSFKLNNCVRHVRIEQDQGTFSFGSYAKFKSQ-----TITEFIEKAVEHSRS---GRYL 936
            ..|:|::|...:....::|||...|.|...|....|.:     ::...:|..|:.||:   ||
Zfish    75 RDYLFTISAMTSAGPTNLRIEYKDGKFKLDSVVLVKPKLKQFDSVVHLVEHYVQLSRTSCKGR-- 137

  Fly   937 FFLHRRPEHGPMRVQLTNPVSRFKHVQSLQHMCRFVILKAVIRKDLIQTLPLPRRLLDYL 996
             .....|.:|.:::.||.||  :....||||:||..|.|...|   :|.||||.||.|||
Zfish   138 -TNQIAPSNGTVQLLLTTPV--YTATPSLQHLCRIAINKTTRR---VQELPLPNRLKDYL 191

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Socs16D	NP_001259662.1	SH2_SOCS7	839..937	CDD:198251	32/106 (30%)
Socs16D	NP_001259662.1	SOCS_SOCS7	960..1009	CDD:239710	19/37 (51%)
socs2	XP_005164804.1	SH2	36..139	CDD:301589	32/105 (30%)
socs2	XP_005164804.1	SOCS_SOCS2	158..198	CDD:239705	19/37 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4566
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810