Protein Alignment Socs16D and Socs6

DIOPT Version :9

• Sequence 1: NP_001259662.1
• Gene: Socs16D / 32760
• FlyBaseID: FBgn0030869
• Length: 1021
• Species: Drosophila melanogaster
• Sequence 2: NP_061291.2
• Gene: Socs6 / 54607
• MGIID: 1924885
• Length: 533
• Species: Mus musculus
• Alignment Length: 631
• Identity: 164/631 - (25%)
• Similarity: 244/631 - (38%)
• Gaps: 155/631 - (24%)

  Fly   421 LSSSHNSLNVSSANKPDDSIFITQAMSHDALFTREISDFYNVPIDSDIYAFPVDMIEQQQQQQLL 485
            |.:...|.|:|. :|.:....:.|..|....|.::.|.|.:        .:..||....     :
Mouse     6 LKTFRKSFNLSK-SKDETEFMVVQPQSLAGDFVKDDSLFGS--------CYGKDMASCD-----I 56

  Fly   486 VEEQQQQKPAAPTYHKASRRNKRNKRKQRYAGSGTGAGTETSDGD--GEKSKHGKYRTPVGVGMG 548
            ..|.::.|..:.:........:|...||:..|.|   ||.::|.|  ...|..|        |:.
Mouse    57 GSEDEKGKNRSKSESLMGTLKRRLSAKQKTKGKG---GTASTDEDTFSSASAPG--------GLK 110

  Fly   549 QVSESEPLHMTLDEVKQFYHTLYSDAGKPTPKPM-VKSSNETIWSVSTNTTTTTARTRSSVGTTR 612
            .|....|:..|         :|.|....|||.|: ..||.||...:.       .|.::.|
Mouse   111 DVRAPRPIRST---------SLRSHHYSPTPWPLRPTSSEETCIKME-------MRVKALV---- 155

  Fly   613 GGGGPPGAGNGAGGASSDGGVGGGSAGGGGGKYLSKQNKHNLDNDKLNNNNNNNNNHQPSQQQLE 677
                         .|:|.|.|.|           .:::...|...:|.:            .|.|
Mouse   156 -------------HAASPGPVNG-----------VRKDLRELQPRELRD------------LQPE 184

  Fly   678 KPPTEHHNQHQPPN-----NKHV-----LHSEKKSQFTLNLKQRFCSIFRFRRSNHSRCRGSGN- 731
            ..|....:...|.:     .:||     |.|:...|:|:.|....|.:    ....|.|..:.:
Mouse   185 PRPESRCSPSSPGDLSLHLEEHVPVVIGLMSQDYLQYTVPLDDGMCPL----EGPRSCCLDTSSP 245

  Fly   732 ---------NQTGTFASANANAAATAPLIPPIAVITSAP----GAAGQTQLASELNGTLITAEAD 783
                     ..:|.|:..:::......:.|.|.|.:|..    |..| ..|.|...|     ..|
Mouse   246 MEVSAVPLPGASGAFSEDDSHVDQDLVVGPEILVDSSVNNLLIGTTG-VMLQSPRGG-----HDD 304

  Fly   784 EP----------NADLRKKFQSRALPPL-------------PKKALPFTAAAYAIEAVKSEPEEV 825
            .|          |..:::.|...:.|.|             |..| |..|..|  ::|:|....|
Mouse   305 APPLSPLLPPMQNNPIQRNFSGLSGPDLHMAESVRCHLNFDPNSA-PGVARVY--DSVQSSGPMV 366

  Fly   826 KTNAIQEPRALQFTSSIEKVKDYGWYWGPLSSEAAEKVLSSEPDGSFIVRDSSDDHYIFSLSFKL 890
            .|:         .|..::|:...||||||::...||..|::.|||||:|||||||.|:.||||:.
Mouse   367 VTS---------LTEELKKLAKQGWYWGPITRWEAEGKLANVPDGSFLVRDSSDDRYLLSLSFRS 422

  Fly   891 NNCVRHVRIEQDQGTFSFGSYAKFKSQT-ITEFIEKAVEHSRSGRYLFFLHRRPEHGPMRVQLTN 954
            :....|.|||...|.|||......:..| |.:.||.::..|.:|.:.:...|.|......|:|||
Mouse   423 HGKTLHTRIEHSNGRFSFYEQPDVEGHTSIVDLIEHSIRDSENGAFCYSRSRLPGSATYPVRLTN 487

  Fly   955 PVSRFKHVQSLQHMCRFVILKAVIRKDLIQTLPLPRRLLDYLNYKH 1000
            |||||..|:|||::||||| :...|.||||.||||.::.|||..||
Mouse   488 PVSRFMQVRSLQYLCRFVI-RQYTRIDLIQKLPLPNKMKDYLQEKH 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Socs16D	NP_001259662.1	SH2_SOCS7	839..937	CDD:198251	42/98 (43%)
		SOCS_SOCS7	960..1009	CDD:239710	23/41 (56%)
Socs6	NP_061291.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	54..136		23/106 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	177..199		5/33 (15%)
		SH2_SOCS6	371..470	CDD:198250	42/98 (43%)
		SOCS_SOCS6	493..533	CDD:239709	23/41 (56%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	74	1.000	Domainoid score	I9103
eggNOG	1	0.900	-	-		E1_KOG4566
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR10155
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3554
SonicParanoid	1	1.000	-	-		X1970
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.940