Protein Alignment Socs16D and SOCS7

DIOPT Version :9

• Sequence 1: NP_001259662.1
• Gene: Socs16D / 32760
• FlyBaseID: FBgn0030869
• Length: 1021
• Species: Drosophila melanogaster
• Sequence 2: NP_055413.2
• Gene: SOCS7 / 30837
• HGNCID: 29846
• Length: 645
• Species: Homo sapiens
• Alignment Length: 444
• Identity: 138/444 - (31%)
• Similarity: 197/444 - (44%)
• Gaps: 97/444 - (21%)

  Fly   636 GSAGGGGGKYLSKQNKHNLD------NDKLNNNNNNNNNHQPSQQQLEKPPTEHHNQHQPPNNKH 694
            |..|||||:.|.:.....|.      .|.:.....:....|..|||...||.      .||....
Human   205 GRGGGGGGRLLLQPPGPELPPVPFPLQDLVPLGRLSRGEQQQQQQQQPPPPP------PPPGPLR 263

  Fly   695 VLHS-EKKSQFTLNLKQRFCSIFRFRRSNHSRCRGSGNNQTGTFASANANAAATAPLIPPIAVIT 758
            .|.. .:|..|.:.|.:    :||.:     .|.|......||....:...||:|      |.:|
Human   264 PLAGPSRKGSFKIRLSR----LFRTK-----SCNGGSGGGDGTGKRPSGELAASA------ASLT 313

  Fly   759 SAPGAAG------------QTQ------------------------------------------- 768
            ...|:||            :||
Human   314 DMGGSAGRELDAGRKPKLTRTQSAFSPVSFSPLFTGETVSLVDVDISQRGLTSPHPPTPPPPPRR 378

  Fly   769 ---LASELNGTLITAEADEPNADLRKKFQSRALPPLP----KKALPFTAAAYAIEAVKSEPEEVK 826
               |..:::|||.|:....|   :....||..|||.|    ..|.|..|...|.|::.|:|.:..
Human   379 SLSLLDDISGTLPTSVLVAP---MGSSLQSFPLPPPPPPHAPDAFPRIAPIRAAESLHSQPPQHL 440

  Fly   827 TNAIQEPRALQFTSSIEKVKDYGWYWGPLSSEAAEKVLSSEPDGSFIVRDSSDDHYIFSLSFKLN 891
            ...:..|.:..|.:|:.:::..||||||::.|.||..|..:|||||:||||||..||.||||:..
Human   441 QCPLYRPDSSSFAASLRELEKCGWYWGPMNWEDAEMKLKGKPDGSFLVRDSSDPRYILSLSFRSQ 505

  Fly   892 NCVRHVRIEQDQGTFSFGSYAKF--KSQTITEFIEKAVEHSRSGRYLFFLHRR-PEHGPMRVQLT 953
            ....|.|:|..:||||...:.||  :.|::.|||::|:.||::|::|:||..| |...|..|||.
Human   506 GITHHTRMEHYRGTFSLWCHPKFEDRCQSVVEFIKRAIMHSKNGKFLYFLRSRVPGLPPTPVQLL 570

  Fly   954 NPVSRFKHVQSLQHMCRFVILKAVIRKDLIQTLPLPRRLLDYLNYKHCYSEQVE 1007
            .|||||.:|:||||:|||.| :.::|.|.|..||||:.|:.|:...:.|..|.|
Human   571 YPVSRFSNVKSLQHLCRFRI-RQLVRIDHIPDLPLPKPLISYIRKFYYYDPQEE 623

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Socs16D	NP_001259662.1	SH2_SOCS7	839..937	CDD:198251	45/99 (45%)
		SOCS_SOCS7	960..1009	CDD:239710	21/48 (44%)
SOCS7	NP_055413.2	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165145603
Domainoid	1	1.000	74	1.000	Domainoid score	I9166
eggNOG	1	0.900	-	-		E1_KOG4566
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0006587
OrthoInspector	1	1.000	-	-		oto91158
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3554
SonicParanoid	1	1.000	-	-		X1970
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	8	7.770