Protein Alignment Socs16D and Cish

DIOPT Version :10

• Sequence 1: NP_001259662.1
• Gene: Socs16D / 32760
• FlyBaseID: FBgn0030869
• Length: 1021
• Species: Drosophila melanogaster
• Sequence 2: XP_006511698.1
• Gene: Cish / 12700
• MGIID: 103159
• Length: 325
• Species: Mus musculus
• Alignment Length: 240
• Identity: 63/240 - (26%)
• Similarity: 96/240 - (40%)
• Gaps: 62/240 - (25%)

  Fly   797 ALPPLPKKALPFTAAAYAIEAVKSEPEEVKTNAIQEPRALQ-------FTSSIEKVKDYGWYWGP 854
            |:.|||..|.|           :...||....|..||:.|.       ...:...:::.|||||.
Mouse   101 AMQPLPTGAFP-----------EEVTEETPVQAENEPKVLDPEGDLLCIAKTFSYLRESGWYWGS 154

  Fly   855 LSSEAAEKVLSSEPDGSFIVRDSSDDHYIFSLSFKLNNCVRHVRIEQDQGTFSFGSYAKFKSQ-- 917
            :::..|.:.|...|:|:|:||||:...|:|:||.|......:||||....:|...|....:.:
Mouse   155 ITASEARQHLQKMPEGTFLVRDSTHPSYLFTLSVKTTRGPTNVRIEYADSSFRLDSNCLSRPRIL 219

  Fly   918 -------TITEFIEKAVEHSRSGRYLFFLHRRPEHGP------------------------MRVQ 951
                   .:..::......:||.        .|:..|                        :.::
Mouse   220 AFPDVVSLVQHYVASCAADTRSD--------SPDPAPTPALPMSKQDAPSDSVLPIPVATAVHLK 276

  Fly   952 LTNPVSRFKHVQSLQHMCRFVILKAVIRKDLIQTLPLPRRLLDYL 996
            |..|..|....:||||:||.||.:.|...|   .||||||:.|||
Mouse   277 LVQPFVRRSSARSLQHLCRLVINRLVADVD---CLPLPRRMADYL 318

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Socs16D	NP_001259662.1	SH2_SOCS7	839..937	CDD:198251	27/106 (25%)
		SOCS_SOCS7	960..1009	CDD:239710	19/37 (51%)
Cish	XP_006511698.1	SH2_CIS	145..232	CDD:198285	25/86 (29%)
		SOCS_CIS1	285..325	CDD:239703	19/37 (51%)