DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Socs16D and cishb

DIOPT Version :9

Sequence 1:	NP_001259662.1	Gene:	Socs16D / 32760	FlyBaseID:	FBgn0030869	Length:	1021	Species:	Drosophila melanogaster
Sequence 2:	XP_017213670.1	Gene:	cishb / 100136861	ZFINID:	ZDB-GENE-080204-120	Length:	213	Species:	Danio rerio

Alignment Length:	200	Identity:	59/200 - (29%)
Similarity:	90/200 - (45%)	Gaps:	33/200 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   819 KSEPEEVKTNAIQEPRALQF-------TSSIEKVKDYGWYWGPLSSEAAEKVLSSEPDGSFIVRD 876
            ::|..|.:....|:.:|..:       |::.:.:...|||||.|::..|...|...|:|:|:|||
Zfish    18 QNERGESEVQQTQQHQAAPYSEDFHFITTTFQHLNTSGWYWGGLTAGDARAALIGAPEGTFLVRD 82

  Fly   877 SSDDHYIFSLSFKLNNCVRHVRIEQDQGTFSFGSYAKFKSQTIT-EFIEKAVEHSRSGRYLFFLH 940
            ||...|:|:||.:......::|||.|.|.|...|....:|..:: ..:...|.|..|.
Zfish    83 SSHPLYLFTLSVQTWRGPTNIRIEYDSGRFRLDSSFPARSCLLSFSALPSLVHHYSSA------- 140

  Fly   941 RRPE-------HGPM-------RVQLTNPVSRFKHVQSLQHMCRFVILKAVIRKDLIQTLPLPRR 991
             |||       |..|       .::|..|:.|.:...:|||:.|..|.:   ..|....|||||.
Zfish   141 -RPEEEKKAEDHHHMVAKDTGILLKLRKPLHRPQAFPTLQHLTRLTINR---HTDCHTKLPLPRP 201

  Fly   992 LLDYL 996
            ||.||
Zfish   202 LLLYL 206

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Socs16D	NP_001259662.1	SH2_SOCS7	839..937	CDD:198251	32/98 (33%)
Socs16D	NP_001259662.1	SOCS_SOCS7	960..1009	CDD:239710	14/36 (39%)
cishb	XP_017213670.1	SH2_CIS	51..138	CDD:198285	30/86 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4566
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	3	2.770