Protein Alignment Socs16D and cish

DIOPT Version :10

• Sequence 1: NP_001259662.1
• Gene: Socs16D / 32760
• FlyBaseID: FBgn0030869
• Length: 1021
• Species: Drosophila melanogaster
• Sequence 2: XP_012816010.1
• Gene: cish / 100135018
• XenbaseID: XB-GENE-490099
• Length: 266
• Species: Xenopus tropicalis
• Alignment Length: 262
• Identity: 69/262 - (26%)
• Similarity: 111/262 - (42%)
• Gaps: 62/262 - (23%)

  Fly   760 APGAAGQTQLASELNGTLITAEADEPNADLRKKFQSRALPPLPKKALPFTAAAYAIEAVKSEPEE 824
            |||.:.. |:...||....|..|..|                             :| |.:..|:
 Frog    35 APGFSAD-QVMHPLNSPACTRPAPNP-----------------------------VE-VPTSTED 68

  Fly   825 VKTNAIQEPRA-------LQFTSSIEKVKDYGWYWGPLSSEAAEKVLSSEPDGSFIVRDSSDDHY 882
            ..||...:.|:       |....:...:::.|||||.:::..|::.|...|:|.|:||||:...|
 Frog    69 SVTNPQPQSRSRDPEADLLCIARTFCYLRESGWYWGSITATEAKQQLQKMPEGFFLVRDSTHPSY 133

  Fly   883 IFSLSFKLNNCVRHVRIEQDQGTFSFGSYAKFKSQTITEF--IEKAVEHSRSGRYLFFLH----R 941
            :|:||.:.|....:||||...|.|...|....|.: |..|  :...|::     |:.|.|    :
 Frog   134 LFTLSVRTNRGPTNVRIEYSDGLFRLDSNCLSKPR-ILSFPDVVSLVQY-----YVSFCHSDVNK 192

  Fly   942 RP------------EHGPMRVQLTNPVSRFKHVQSLQHMCRFVILKAVIRKDLIQTLPLPRRLLD 994
            .|            |...:.::|.:|:.|.....||||:||..|.:::.....:..||||||:::
 Frog   193 EPACQTPPVPPSPKEPAAVHLKLLHPLPRGAQCPSLQHLCRLQINRSLAPNAELTELPLPRRMVE 257

  Fly   995 YL 996
            ||
 Frog   258 YL 259

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Socs16D	NP_001259662.1	SH2_SOCS7	839..937	CDD:198251	31/99 (31%)
		SOCS_SOCS7	960..1009	CDD:239710	15/37 (41%)
cish	XP_012816010.1	SH2_CIS	96..183	CDD:198285	30/92 (33%)
		SOCS	226..266	CDD:470605	15/34 (44%)