Protein Alignment PRMT1 and Art1

DIOPT Version :10

• Sequence 1: NP_001527.3
• Gene: PRMT1 / 3276
• HGNCID: 5187
• Length: 371
• Species: Homo sapiens
• Sequence 2: NP_650017.1
• Gene: Art1 / 41295
• FlyBaseID: FBgn0037834
• Length: 376
• Species: Drosophila melanogaster
• Alignment Length: 372
• Identity: 242/372 - (65%)
• Similarity: 302/372 - (81%)
• Gaps: 7/372 - (1%)

Human     2 AAAEAANCIMENFVATLANGMSLQPPLEEVSCGQAESSEKPNAEDMTSKDYYFDSYAHFGIHEEM 66
            ||.|:|..|..|..|. :|.::.:.|.|    |....:...||::|||:||||||||||||||||
  Fly    10 AAVESATGITPNSNAN-SNNVAKKLPAE----GSTGDNPNANADEMTSRDYYFDSYAHFGIHEEM 69

Human    67 LKDEVRTLTYRNSMFHNRHLFKDKVVLDVGSGTGILCMFAAKAGARKVIGIECSSISDYAVKIVK 131
            |||||||:||||:|:||:|||:.|.|||||.|||||.||||||||.:||.::||:|.::|.::|.
  Fly    70 LKDEVRTVTYRNAMYHNKHLFQGKTVLDVGCGTGILSMFAAKAGAAQVIAVDCSNIIEFARQVVI 134

Human   132 ANKLDHVVTIIKGKVEEVELP--VEKVDIIISEWMGYCLFYESMLNTVLYARDKWLAPDGLIFPD 194
            .|.|..|:|::|||:||:|||  :|.|||||||||||||||||||:||||||||||..||::|||
  Fly   135 DNNLQDVITVVKGKIEEIELPNGIEGVDIIISEWMGYCLFYESMLDTVLYARDKWLKKDGMMFPD 199

Human   195 RATLYVTAIEDRQYKDYKIHWWENVYGFDMSCIKDVAIKEPLVDVVDPKQLVTNACLIKEVDIYT 259
            |.|||:||||||||||.||:||::|||||||||:.||:.|||||||||||:|:.:|::||||:||
  Fly   200 RGTLYITAIEDRQYKDEKINWWDDVYGFDMSCIRKVAVTEPLVDVVDPKQVVSTSCMVKEVDLYT 264

Human   260 VKVEDLTFTSPFCLQVKRNDYVHALVAYFNIEFTRCHKRTGFSTSPESPYTHWKQTVFYMEDYLT 324
            |:..||.|:|.|.|.:||||:|.|||.|||||||:||||.||||||:|.||||||||||::|::|
  Fly   265 VQKADLNFSSKFSLCIKRNDFVQALVTYFNIEFTKCHKRLGFSTSPDSTYTHWKQTVFYLDDHMT 329

Human   325 VKTGEEIFGTIGMRPNAKNNRDLDFTIDLDFKGQLCELSCSTDYRMR 371
            .|..|||.||..|:||.:|||||||.||::|||:|.::..|..||||
  Fly   330 AKKNEEITGTFQMKPNERNNRDLDFVIDINFKGELSQIQESNTYRMR 376

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PRMT1	NP_001527.3	COG4076	63..>236	CDD:443253	124/174 (71%)
Art1	NP_650017.1	COG4076	66..>231	CDD:443253	118/164 (72%)