Protein Alignment OdsH and PRRX2

DIOPT Version :10

• Sequence 1: NP_523389.3
• Gene: OdsH / 32758
• FlyBaseID: FBgn0026058
• Length: 382
• Species: Drosophila melanogaster
• Sequence 2: NP_057391.1
• Gene: PRRX2 / 51450
• HGNCID: 21338
• Length: 253
• Species: Homo sapiens
• Alignment Length: 298
• Identity: 74/298 - (24%)
• Similarity: 112/298 - (37%)
• Gaps: 86/298 - (28%)

  Fly    31 AAAAAVNMQVSGWSSVLNLSMDAPNPEISPNSVTNSSSVYMIRQMALIQQARVAAAAVAMQQQQQ 95
            :||||..:.    ...|......|.|.:.|.....:...:.:..:..:::...|....|....:.
Human     3 SAAAAFALD----KPALGPGPPPPPPALGPGDCAQARKNFSVSHLLDLEEVAAAGRLAARPGARA 63

  Fly    96 QQRDLNRELGMDPHSEQRIKLDSVSPTHNIHAGSSRGIKQDPLSDEGADSNLGQNDCTESSKK-R 159
            :.|:   ....:|                  :|.|.|.:..|  .:|...:.|:....:..|| |
Human    64 EARE---GAAREP------------------SGGSSGSEAAP--QDGECPSPGRGSAAKRKKKQR 105

  Fly   160 RGRTNFNSWQLRELERVFQGSHYPDIFMREALATKLDLMEGRIAVWFQNRRAKWRKQEHTKKGPG 224
            |.||.|||.||:.|||||:.:||||.|:||.||.:::|.|.|:.|||||||||:|:.|...
Human   106 RNRTTFNSSQLQALERVFERTHYPDAFVREELARRVNLSEARVQVWFQNRRAKFRRNERAM---- 166

  Fly   225 RPAHNAHPQSCSGDPIPLSELRARELAQRSKRMKKAIDRQAKKLQDKGLEVDYA----RLEAEYL 285
                                     ||.||..:.|:..::|      .:|...|    .|..:||
Human   167 -------------------------LASRSASLLKSYSQEA------AIEQPVAPRPTALSPDYL 200

  Fly   286 AAHQENGVDENNWLDDDGYDDLHIDVVGVEPEYVTGDS 323
                       :|.....|..:        |.|..|.|
Human   201 -----------SWTASSPYSTV--------PPYSPGSS 219

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
OdsH	NP_523389.3	Homeodomain	159..215	CDD:459649	35/55 (64%)
PRRX2	NP_057391.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..33		8/33 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	55..113		16/80 (20%)
		Homeodomain	109..161	CDD:459649	32/51 (63%)
		OAR. /evidence=ECO:0000255|PROSITE-ProRule:PRU00138	230..243