Protein Alignment OdsH and VSX2

DIOPT Version :10

• Sequence 1: NP_523389.3
• Gene: OdsH / 32758
• FlyBaseID: FBgn0026058
• Length: 382
• Species: Drosophila melanogaster
• Sequence 2: NP_878314.1
• Gene: VSX2 / 338917
• HGNCID: 1975
• Length: 361
• Species: Homo sapiens
• Alignment Length: 288
• Identity: 83/288 - (28%)
• Similarity: 116/288 - (40%)
• Gaps: 102/288 - (35%)

  Fly    95 QQQRDLNRELGMDPHSEQRIKLDSVSPTHNIHA-----------------GSSRGIKQDP----- 137
            |:...||:|   .|.|..|..||.::|.|.:.|                 |...|....|
Human    35 QEILGLNKE---PPSSHPRAALDGLAPGHLLAARSVLSPAGVGGMGLLGPGGLPGFYTQPTFLEV 96

  Fly   138 LSD-----------------------------EGADSNLGQN--DCTESSKKRRGRTNFNSWQLR 171
            |||                             ..:|..:.::  :.|:..||||.||.|.|:||.
Human    97 LSDPQSVHLQPLGRASGPLDTSQTASSDSEDVSSSDRKMSKSALNQTKKRKKRRHRTIFTSYQLE 161

  Fly   172 ELERVFQGSHYPDIFMREALATKLDLMEGRIAVWFQNRRAKWRKQEHTKKGPGRPA--------- 227
            |||:.|..:||||::.||.||.|.:|.|.||.||||||||||||:|   |..||.:
Human   162 ELEKAFNEAHYPDVYAREMLAMKTELPEDRIQVWFQNRRAKWRKRE---KCWGRSSVMAEYGLYG 223

  Fly   228 ----HNAHPQSCSGDPIPLSELRARE-----------LAQRSKRMKKAI--------DRQAKKLQ 269
                |:.        |:|.|.|::.:           |....|.::.|.        :|||....
Human   224 AMVRHSI--------PLPESILKSAKDGIMDSCAPWLLGMHKKSLEAAAESGRKPEGERQALPKL 280

  Fly   270 DKGLEVDYARLEAEYLAAHQENGVDENN 297
            || :|.|....:|:  ||..:..:.||:
Human   281 DK-MEQDERGPDAQ--AAISQEELRENS 305

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
OdsH	NP_523389.3	Homeodomain	159..215	CDD:459649	35/55 (64%)
VSX2	NP_878314.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..28
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	104..151		5/46 (11%)
		Homeodomain	153..205	CDD:459649	32/51 (63%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	262..300		11/40 (28%)
		OAR	300..318	CDD:461067	2/6 (33%)
		OAR. /evidence=ECO:0000255|PROSITE-ProRule:PRU00138	304..317		1/2 (50%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	313..361