DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment OdsH and vsx1

DIOPT Version :9

Sequence 1:	NP_523389.3	Gene:	OdsH / 32758	FlyBaseID:	FBgn0026058	Length:	382	Species:	Drosophila melanogaster
Sequence 2:	NP_571408.1	Gene:	vsx1 / 30598	ZFINID:	ZDB-GENE-990415-205	Length:	344	Species:	Danio rerio

Alignment Length:	343	Identity:	89/343 - (25%)
Similarity:	133/343 - (38%)	Gaps:	107/343 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 LIQQLQQAAAARGQVQHPHGSSALQLYAAAAAVNMQVSGWSSVLNL----SMDAPNPEISPNSVT 64
            |..:||...:..|...:..|.|       ||.......|.|..|.|    |:.|..|..:|
Zfish    45 LESELQPHQSGPGAGPNGEGQS-------AAVGGFSFPGGSLPLGLGFLCSLAAQQPPGAP---- 98

  Fly    65 NSSSVYMIRQMALIQQARVAAAAVAMQQQQQQQRDLNRELGMDPHSEQRIKLDSVSPTHNIHAGS 129
                .::...:.|:|    :.......|..:||||:..:
Zfish    99 ----CFLPSHIPLLQ----SRTESHFMQNLEQQRDVYSD-------------------------- 129

  Fly   130 SRGIKQDPLSDEGADSNLGQND-CTESSKKRRGRTNFNSWQLRELERVFQGSHYPDIFMREALAT 193
                 .|.||   .|.|.|:|. .::..||||.||.|.|.||.|||:.|..:||||::.||.||.
Zfish   130 -----DDCLS---GDRNDGKNSGNSQKRKKRRHRTVFTSHQLEELEKAFNEAHYPDVYAREMLAM 186

  Fly   194 KLDLMEGRIAVWFQNRRAKWRKQEHTKKGPGRPAHNAH--------------PQ----------- 233
            |.:|.|.||.||||||||||||:|   |..||.:..|.              |:
Zfish   187 KTELPEDRIQVWFQNRRAKWRKRE---KCWGRSSVMAEYGLYGAMVRHSIPLPESIINSAKSGMM 248

  Fly   234 -SCS----GDPIPLSELRARELAQRSKRMKKAIDRQAKKLQDKGLEVDYARLEAEYLAAHQENGV 293
             ||:    |:|..:.: ::.|:.:::....::........:.||.:.|..       .:...||.
Zfish   249 GSCAPWLLGEPAGMHK-KSMEIVKKAPGTPESTHSDTYSEEHKGKDSDTT-------WSSGANGA 305

  Fly   294 DENNWLDDDGYDDLHIDV 311
            |::        :|:.||:
Zfish   306 DDS--------EDMAIDL 315

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
OdsH	NP_523389.3	Homeobox	162..214	CDD:278475	32/51 (63%)
vsx1	NP_571408.1	Octapeptide motif	37..44
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	49..70		7/27 (26%)
		COG5576	101..>221	CDD:227863	57/160 (36%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	127..156		11/62 (18%)
		Nuclear localization signal. /evidence=ECO:0000269\|PubMed:11331779	147..151		0/3 (0%)
		Homeobox	154..207	CDD:278475	32/52 (62%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	273..344		9/58 (16%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910