DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment OdsH and Uncx

DIOPT Version :9

Sequence 1:	NP_523389.3	Gene:	OdsH / 32758	FlyBaseID:	FBgn0026058	Length:	382	Species:	Drosophila melanogaster
Sequence 2:	NP_058875.2	Gene:	Uncx / 29375	RGDID:	69361	Length:	530	Species:	Rattus norvegicus

Alignment Length:	362	Identity:	115/362 - (31%)
Similarity:	149/362 - (41%)	Gaps:	152/362 - (41%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 QLQQAAAARGQVQHPHGSSALQLYAAAAAVNMQVSGWSSVLNLSMDAPNPEISPNSVTNSSSVYM 71
            |||.||||                ||||:|...:.|
  Rat    40 QLQSAAAA----------------AAAASVPFSIDG----------------------------- 59

  Fly    72 IRQMALIQQARVAAAAVAMQQQQQQQRDLNRELGMDPHSEQRIKLDSVSPTHNIH-----AGSSR 131
                 |:..:..||||                             ..|:||..:.     ||.|:
  Rat    60 -----LLSGSCAAAAA-----------------------------SVVNPTPLLPAACGVAGESQ 90

  Fly   132 GIKQDPLSDEGADSNLGQNDCTESSKKRRGRTNFNSWQLRELERVFQGSHYPDIFMREALATKLD 196
            ..|   |:|.| |.:.....|    |:||.||||..|||.|||:.|..|||||:|||||||.:||
  Rat    91 PFK---LADSG-DPDKESPGC----KRRRTRTNFTGWQLEELEKAFNESHYPDVFMREALALRLD 147

  Fly   197 LMEGRIAVWFQNRRAKWRKQEHTKKGPGRPAHNAHPQSCSGDPIPLSELRARELAQRSKRMKKAI 261
            |:|.|:.||||||||||||:|:|||||||||||:||.:|||:|:...|:..:||.:..|:.:|
  Rat   148 LVESRVQVWFQNRRAKWRKKENTKKGPGRPAHNSHPTTCSGEPMDPEEIARKELEKMEKKKRK-- 210

  Fly   262 DRQAKKLQDKGLEVDYARLEAEYLAAHQENGVDENNWLDDDGYDDLHIDVVGVEPEYVTGDSLDH 326
              ..|||           |:::....|...|:            .||
  Rat   211 --HEKKL-----------LKSQSRHLHSPGGL------------SLH------------------ 232

  Fly   327 SFCSSRTYQTKSTSSELDSNDMGLQGRVETPPPPQPP 363
                      .:.||:.||...||     :|.||:||
  Rat   233 ----------SAPSSDSDSGGGGL-----SPEPPEPP 254

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
OdsH	NP_523389.3	Homeobox	162..214	CDD:278475	37/51 (73%)
Uncx	NP_058875.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	90..111		7/28 (25%)
		Homeobox	112..166	CDD:395001	38/53 (72%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	165..362		44/150 (29%)
		PHA03247	<289..524	CDD:223021
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	400..530
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BD9D
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	173	1.000	Inparanoid score	I3988
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004658
OrthoInspector	1	1.000	-	-		otm45223
orthoMCL	1	0.900	-	-		OOG6_108739
Panther	1	1.100	-	-	O	PTHR46799
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X4373
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	10	9.820