DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment OdsH and Uncx

DIOPT Version :9

Sequence 1:	NP_523389.3	Gene:	OdsH / 32758	FlyBaseID:	FBgn0026058	Length:	382	Species:	Drosophila melanogaster
Sequence 2:	NP_038730.1	Gene:	Uncx / 22255	MGIID:	108013	Length:	530	Species:	Mus musculus

Alignment Length:	362	Identity:	115/362 - (31%)
Similarity:	149/362 - (41%)	Gaps:	152/362 - (41%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 QLQQAAAARGQVQHPHGSSALQLYAAAAAVNMQVSGWSSVLNLSMDAPNPEISPNSVTNSSSVYM 71
            |||.||||                ||||:|...:.|
Mouse    40 QLQSAAAA----------------AAAASVPFSIDG----------------------------- 59

  Fly    72 IRQMALIQQARVAAAAVAMQQQQQQQRDLNRELGMDPHSEQRIKLDSVSPTHNIH-----AGSSR 131
                 |:..:..||||                             ..|:||..:.     ||.|:
Mouse    60 -----LLSGSCAAAAA-----------------------------SVVNPTPLLPAACGVAGESQ 90

  Fly   132 GIKQDPLSDEGADSNLGQNDCTESSKKRRGRTNFNSWQLRELERVFQGSHYPDIFMREALATKLD 196
            ..|   |:|.| |.:.....|    |:||.||||..|||.|||:.|..|||||:|||||||.:||
Mouse    91 PFK---LADSG-DPDKESPGC----KRRRTRTNFTGWQLEELEKAFNESHYPDVFMREALALRLD 147

  Fly   197 LMEGRIAVWFQNRRAKWRKQEHTKKGPGRPAHNAHPQSCSGDPIPLSELRARELAQRSKRMKKAI 261
            |:|.|:.||||||||||||:|:|||||||||||:||.:|||:|:...|:..:||.:..|:.:|
Mouse   148 LVESRVQVWFQNRRAKWRKKENTKKGPGRPAHNSHPTTCSGEPMDPEEIARKELEKMEKKKRK-- 210

  Fly   262 DRQAKKLQDKGLEVDYARLEAEYLAAHQENGVDENNWLDDDGYDDLHIDVVGVEPEYVTGDSLDH 326
              ..|||           |:::....|...|:            .||
Mouse   211 --HEKKL-----------LKSQSRHLHSPGGL------------SLH------------------ 232

  Fly   327 SFCSSRTYQTKSTSSELDSNDMGLQGRVETPPPPQPP 363
                      .:.||:.||...||     :|.||:||
Mouse   233 ----------SAPSSDSDSGGGGL-----SPEPPEPP 254

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
OdsH	NP_523389.3	Homeobox	162..214	CDD:278475	37/51 (73%)
Uncx	NP_038730.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	90..111		7/28 (25%)
		Homeobox	112..165	CDD:278475	37/52 (71%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	165..360		44/150 (29%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	400..530
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004658
OrthoInspector	1	1.000	-	-		otm43154
orthoMCL	1	0.900	-	-		OOG6_108739
Panther	1	1.100	-	-	O	PTHR46799
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5708
SonicParanoid	1	1.000	-	-		X4373
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.940