Protein Alignment OdsH and Pitx2

DIOPT Version :10

• Sequence 1: NP_523389.3
• Gene: OdsH / 32758
• FlyBaseID: FBgn0026058
• Length: 382
• Species: Drosophila melanogaster
• Sequence 2: NP_001035967.1
• Gene: Pitx2 / 18741
• MGIID: 109340
• Length: 324
• Species: Mus musculus
• Alignment Length: 323
• Identity: 83/323 - (25%)
• Similarity: 128/323 - (39%)
• Gaps: 91/323 - (28%)

  Fly    85 AAAVAMQQQQQQQRDLNRELGMDPHSEQRIKLDSVSPTHNIHAGSSRGIKQDPLSDEGADSNLGQ 149
            |.|:|......|.|.|:       .|:.|:::.::|.|      ||..:.:.....:|.:.::|.
Mouse    32 ALAMASVLAPGQPRSLD-------SSKHRLEVHTISDT------SSPEVAEKDKGQQGKNEDVGA 83

  Fly   150 NDCTESSKKRRGRTNFNSWQLRELERVFQGSHYPDIFMREALATKLDLMEGRIAVWFQNRRAKWR 214
            .|.::..::||.||:|.|.||:|||..||.:.|||:..||.:|...:|.|.|:.|||:|||||||
Mouse    84 EDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWR 148

  Fly   215 KQEHTKKGPGRPAHNAHPQSCSGDPIPLSELRARELAQRSKRMKKAIDRQAKKLQDKGLEVDYAR 279
            |:|          .|...:.|.....|                           |..||...|..
Mouse   149 KRE----------RNQQAELCKNGFGP---------------------------QFNGLMQPYDD 176

  Fly   280 LEAEYLAAHQENGVDENNW---------LDDDG---YDDLHIDVVGVE-----PEYVTGDSLDHS 327
            :..         |...|||         |....   ::.::::.:..:     |..::..|:..|
Mouse   177 MYP---------GYSYNNWAAKGLTSASLSTKSFPFFNSMNVNPLSSQSMFSPPNSISSMSMSSS 232

  Fly   328 FCSSRTYQTKSTSSELDS----NDM---GLQGRVETP----PPPQPPMQNKTLYNSPFSIESL 379
            ...|..  |....|.|:|    |::   .|...|.||    .||.||...:...||  |:.||
Mouse   233 MVPSAV--TGVPGSSLNSLNNLNNLSSPSLNSAVPTPACPYAPPTPPYVYRDTCNS--SLASL 291

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
OdsH	NP_523389.3	Homeodomain	159..215	CDD:459649	31/55 (56%)
Pitx2	NP_001035967.1	Homeodomain	93..149	CDD:459649	31/55 (56%)
		OAR	282..299	CDD:461067	5/12 (42%)