Protein Alignment OdsH and Pitx1

DIOPT Version :10

• Sequence 1: NP_523389.3
• Gene: OdsH / 32758
• FlyBaseID: FBgn0026058
• Length: 382
• Species: Drosophila melanogaster
• Sequence 2: NP_035227.1
• Gene: Pitx1 / 18740
• MGIID: 107374
• Length: 315
• Species: Mus musculus
• Alignment Length: 290
• Identity: 82/290 - (28%)
• Similarity: 104/290 - (35%)
• Gaps: 99/290 - (34%)

  Fly   117 DSVSPTHNIHAGSS--------RGIKQDPLSDEGADS---NLGQNDCTESSKKRRGRTNFNSWQL 170
            |...|..|..:.||        ||.:.....|.||.|   ..|..|..:..|:||.||:|.|.||
Mouse    38 DPREPLENSASESSDADLPDKERGGEAKGPEDGGAGSAGCGGGAEDPAKKKKQRRQRTHFTSQQL 102

  Fly   171 RELERVFQGSHYPDIFMREALATKLDLMEGRIAVWFQNRRAKWRKQEHTKKGPGRPAHNAHPQSC 235
            :|||..||.:.|||:.|||.:|...:|.|.|:.|||:||||||||:|          .|.....|
Mouse   103 QELEATFQRNRYPDMSMREEIAVWTNLTEPRVRVWFKNRRAKWRKRE----------RNQQLDLC 157

  Fly   236 SGDPIPLSELRARELAQRSKRMKKAIDRQAKKLQDKGLEVDYARLEAEYLAAHQENGVDENNWLD 300
            .|..:|                           |..||...|   |..|.|     |...|||
Mouse   158 KGGYVP---------------------------QFSGLVQPY---EDVYAA-----GYSYNNW-- 185

  Fly   301 DDGYDDLHIDVVGVEPEYVTGDSLDHSFCSSRTYQTKSTSSELDSNDMGLQGRVETP-------- 357
                               ...||..:..|::::...::.|.|.|..|     ...|
Mouse   186 -------------------AAKSLAPAPLSTKSFTFFNSMSPLSSQSM-----FSAPSSISSMTM 226

  Fly   358 -----PPPQPPMQNKTLYNSPFSIESLLGS 382
                 |...|.|.|..|.|    |.:|.||
Mouse   227 PSSMGPGAVPGMPNSGLNN----INNLTGS 252

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
OdsH	NP_523389.3	Homeodomain	159..215	CDD:459649	32/55 (58%)
Pitx1	NP_035227.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..104		22/65 (34%)
		Homeodomain	91..147	CDD:459649	32/55 (58%)
		Interaction with PIT-1	151..280		33/167 (20%)
		OAR	277..294	CDD:461067
		OAR. /evidence=ECO:0000255|PROSITE-ProRule:PRU00138	281..294
		Nuclear localization signal. /evidence=ECO:0000255	287..291