Protein Alignment unc-4 and ISX

DIOPT Version :10

• Sequence 1: NP_573242.2
• Gene: unc-4 / 32757
• FlyBaseID: FBgn0024184
• Length: 588
• Species: Drosophila melanogaster
• Sequence 2: NP_001290437.1
• Gene: ISX / 91464
• HGNCID: 28084
• Length: 245
• Species: Homo sapiens
• Alignment Length: 94
• Identity: 43/94 - (45%)
• Similarity: 55/94 - (58%)
• Gaps: 8/94 - (8%)

  Fly   216 PAGPPSEGSNEDGGFPGDG------DDDSSAAK-RRRSRTNFNSWQLEELERAFSASHYPDIFMR 273
            |.||..||..| ....|.|      |......| :||.||.|.:.||.|||:.|..:||||:.:|
Human    49 PEGPGEEGPGE-AAASGSGLEKPPKDQPQEGRKSKRRVRTTFTTEQLHELEKIFHFTHYPDVHIR 112

  Fly   274 EALAMRLDLKESRVAVWFQNRRAKVRKRE 302
            ..||.|::|.|:||.:||||:|||.||:|
Human   113 SQLAARINLPEARVQIWFQNQRAKWRKQE 141

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
unc-4	NP_573242.2	Homeodomain	244..300	CDD:459649	30/55 (55%)
ISX	NP_001290437.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	38..86		12/37 (32%)
		Homeodomain	83..139	CDD:459649	30/55 (55%)