Protein Alignment unc-4 and uncx

DIOPT Version :10

• Sequence 1: NP_573242.2
• Gene: unc-4 / 32757
• FlyBaseID: FBgn0024184
• Length: 588
• Species: Drosophila melanogaster
• Sequence 2: XP_005164261.1
• Gene: uncx / 798510
• ZFINID: ZDB-GENE-080509-1
• Length: 483
• Species: Danio rerio
• Alignment Length: 456
• Identity: 149/456 - (32%)
• Similarity: 199/456 - (43%)
• Gaps: 120/456 - (26%)

  Fly   176 LSAAALRNVSAAQTTAVAAVASTVATIQH---RLMIGNRQSLPPAGPPSEGSNEDGGF--PGDGD 235
            ||...:..::..|..:.|||..::..:.:   ...:.|...|..:|....|.|:....  .||.|
Zfish    28 LSHHHVYELAGHQLQSTAAVPFSIDGLLNGSCTASVVNSNPLLSSGCGMNGDNQQYKLTDSGDPD 92

  Fly   236 DDSSAAKRRRSRTNFNSWQLEELERAFSASHYPDIFMREALAMRLDLKESRVAVWFQNRRAKVRK 300
            .||...||||:||||..|||||||:||:.|||||:|||||||:||||.||||.|||||||||.||
Zfish    93 KDSPGCKRRRTRTNFTGWQLEELEKAFNESHYPDVFMREALALRLDLIESRVQVWFQNRRAKWRK 157

  Fly   301 REHTKKGPGRPAHNAQPQTCSGEPIPPNELKAKERARRRKKLAKAIDRQARKLQAKGITVDLEAL 365
            :|:|||||||||||:.|.||||||:.|.|:..:|..|..||..|. :|:..|.|.|.:..||
Zfish   158 KENTKKGPGRPAHNSHPTTCSGEPMDPEEIARRELERLEKKKRKQ-ERRLLKSQNKLLPGDL--- 218

  Fly   366 KAEYISQHKANGTFSDSDLEDDGIQIDVVGGTDSDDEGDSDAVSPVRLGGGGGGGGGTGGGGGGG 430
                   ....|:.|||.|.    ||     |||:
Zfish   219 -------FHTPGSDSDSGLS----QI-----TDSE------------------------------ 237

  Fly   431 ASSSLHCGL--------------------DGDGDSSRAGSFIGGGGSLGSPSSVAPPSMLSN--- 472
              .||||.:                    :.|.|:|        |..|.|..|....::.||
Zfish   238 --QSLHCDMGRNQTQPSCDQTPQKLQNQRNADQDAS--------GSELDSSDSGQQSNLCSNSRS 292

  Fly   473 GAVQFGKLEP--MDGNESEERDRER---DSPKPLLFPAKAFHQLNLQSSQQHHGLVVGQ------ 526
            .|:|  ||.|  ::...|:.|.|.:   |.|.|...|........|....|..|.:|.|
Zfish   293 SALQ--KLNPFSVESLLSDSRPRRKPPMDFPVPTPRPLIGKGHFLLYPITQPLGFIVPQTALKST 355

  Fly   527 GQGSGSGHGH-------------GHQHNHHQHHLHHGSASASAAAAVANLVHQTSPI--SMRRSN 576
            ..|..:.:|.             ||::....:.:::.    |.|.|:...|.|:..|  |.:.|:
Zfish   356 APGPDTENGQKGPATDITFAGNPGHRNAKENNSVNNN----SGARAIKGQVSQSGNISCSTQSSS 416

  Fly   577 P 577
            |
Zfish   417 P 417

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
unc-4	NP_573242.2	Homeodomain	244..300	CDD:459649	44/55 (80%)
uncx	XP_005164261.1	COG5576	<88..208	CDD:227863	80/120 (67%)
		Homeodomain	101..157	CDD:459649	44/55 (80%)