Protein Alignment unc-4 and toy

DIOPT Version :10

• Sequence 1: NP_573242.2
• Gene: unc-4 / 32757
• FlyBaseID: FBgn0024184
• Length: 588
• Species: Drosophila melanogaster
• Sequence 2: NP_001368990.1
• Gene: toy / 43833
• FlyBaseID: FBgn0019650
• Length: 655
• Species: Drosophila melanogaster
• Alignment Length: 652
• Identity: 136/652 - (20%)
• Similarity: 205/652 - (31%)
• Gaps: 265/652 - (40%)

  Fly    66 QHLLGGSP-SSACSTSVSGCGMPSE-------GLH------PTAALQLYAAAAQLAPNGVRVPPW 116
            :|::.|.| ||...:::.||.....       |::      |.:..|   ...:||.:|.|....
  Fly     6 EHIMHGHPHSSVGQSTLFGCSTAGHSGINQLGGVYVNGRPLPDSTRQ---KIVELAHSGARPCDI 67

  Fly   117 GPFLQFGVPGVFGPNG---PFLGR--------PRFDAASAGGHPNSAAAAAAATQMAAV--NASN 168
            ...||..       ||   ..|||        ||    :.||.....|......::|..  ...:
  Fly    68 SRILQVS-------NGCVSKILGRYYETGSIKPR----AIGGSKPRVATTPVVQKIADYKRECPS 121

  Fly   169 AFA----------------NLTGLSA--AALRNVSAAQTTAVAAVASTVATIQHRLMIGNRQ--- 212
            .||                |:..:|:  ..|||: |:|....|...:  .::..:|.:.|.|
  Fly   122 IFAWEIRDRLLSEQVCNSDNIPSVSSINRVLRNL-ASQKEQQAQQQN--ESVYEKLRMFNGQTGG 183

  Fly   213 -------------SLPPAG-------------------------------PPSEGSNEDGG--FP 231
                         :||||.                               ..|..|..||.  ..
  Fly   184 WAWYPSNTTTAHLTLPPAASVVTSPANLSGQADRDDVQKRELQFSVEVSHTNSHDSTSDGNSEHN 248

  Fly   232 GDGDDDSS-----AAKRRRSRTNFNSWQLEELERAFSASHYPDIFMREALAMRLDLKESRVAVWF 291
            ..||:||.     ..|.:|:||:|::.|::.||:.|..:||||:|.||.||.::.|.|:|:.|||
  Fly   249 SSGDEDSQMRLRLKRKLQRNRTSFSNEQIDSLEKEFERTHYPDVFARERLADKIGLPEARIQVWF 313

  Fly   292 QNRRAKVRKREHTKKGPGRPAHNAQPQTCSGEPIPPNELKAKERARRRKKLAKAIDRQARKLQA- 355
            .|||||.|:.|                              |.|.:||.  |..:|...|...|
  Fly   314 SNRRAKWRREE------------------------------KMRTQRRS--ADTVDGSGRTSTAN 346

  Fly   356 --KGITVDLEALKAEYISQHKANGTFSDSDLEDDGIQIDVVGGTDSDDEGDSDAVSPVRLGGGGG 418
              .|.|               |:.:.:.|:....||    |....:..|..|.|:
  Fly   347 NPSGTT---------------ASSSVATSNNSTPGI----VNSAINVAERTSSAL---------- 382

  Fly   419 GGGGTGGGGGGGASSSLHCGLDGDGDSSRAGSFIGGGGSLGSPSSVAPP---------------- 467
                        .|:||       .::|...:.:||..:....||.:||
  Fly   383 ------------VSNSL-------PEASNGPTVLGGEANTTHTSSESPPLQPAAPRLPLNSGFNT 428

  Fly   468 ----------SMLSNGAVQFGKLEPMDGNESEERDRERDSPKPLLFPAKAFHQLNLQSSQQHHGL 522
                      :|..|.....|.:.|   :..::||         .:|......|:|
  Fly   429 MYSSIPQPIATMAENYNSSLGSMTP---SCLQQRD---------AYPYMFHDPLSL--------- 472

  Fly   523 VVGQGQGSGSGHGHGHQHN-------HHQHHLHHGSASASAAAAVANLVHQTSPISMRRSNPFSI 580
                    ||.:...|..|       .||....||..:.|:....:|    |..||...|.|..|
  Fly   473 --------GSPYVSAHHRNTACNPSAAHQQPPQHGVYTNSSPMPSSN----TGVISAGVSVPVQI 525

  Fly   581 ES 582
            .:
  Fly   526 ST 527

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
unc-4	NP_573242.2	Homeodomain	244..300	CDD:459649	28/55 (51%)
toy	NP_001368990.1	PAX	29..153	CDD:128645	24/137 (18%)
		COG5576	<253..368	CDD:227863	47/165 (28%)
		Homeodomain	267..322	CDD:459649	28/54 (52%)